Results 121 to 130 of about 150,893 (291)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Computer-assisted surgery versus manual total knee arthroplasty: A case-controlled study

Zdravniški Vestnik, 2009
Background: Restoration of neutral alignment of the leg is an important factor affecting the long-term results of total knee arthroplasty. Despite the use of modern instruments in total knee arthroplasty, component malalignment remains a problem ...
Simon Kovač, Matevž Topolovec, Vesna Levašič   +2 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Development of a synthetic phantom for the selection of optimal scanning parameters in CAD-CT colonography

, 2006
The aim of this paper is to present the development of a synthetic phantom that can be used for the selection of optimal scanning parameters in computed tomography (CT) colonography. In this paper we attempt to evaluate the influence of the main scanning
Shane Foley, Chowdhury, Tarik A., Ovidiu Ghita, Foley, Shane J., Paul F. Whelan, Nicolas Sezille, Ghita, Ovidiu, Sezille, Ncolas, Sezille, Nicolas, Tarik A. Chowdhury, Foley, Shane, Whelan, Paul F.   +11 more
core   +1 more source

A Comprehensive Computer-Assisted Diagnosis System for Early Assessment of Renal Cancer Tumors. [PDF]

Sensors (Basel), 2021
Shehata M, Alksas A, Abouelkheir RT, Elmahdy A, Shaffie A, Soliman A, Ghazal M, Abu Khalifeh H, Salim R, Abdel Razek AAK, Alghamdi NS, El-Baz A.   +11 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Mammographic Density Assessment by Artificial Intelligence-Based Computer-Assisted Diagnosis: A Comparison with Automated Volumetric Assessment. [PDF]

J Digit Imaging, 2022
Lee SE, Son NH, Kim MH, Kim EK.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Multi-stage deep learning architecture for carotid artery segmentation and stenosis evaluation: comparative study with digital subtraction angiography

Journal of Cardiovascular Magnetic Resonance
Background: High-resolution magnetic resonance imaging (HR-MRI) provides a non-invasive, radiation-free approach for evaluating stenosis caused by carotid atherosclerosis. However, manual recognition is time-consuming and inter-observer variability.
Zhiji Zheng, Wanchen Liu, Zhimeng Cui, Hui Fang, Xiao Liu, Kangyi Pan, Qingqing Lu, Kun Zhou, Xiao Luo, Xin Cao, Daoying Geng   +10 more
doaj   +1 more source