Results 121 to 130 of about 271,239 (323)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Using the ADDIE Model to Nurture the Development of Teachers’ CALL Professional Knowledge

Educational Technology & Society, 2019
Although teacher training programs can deliver knowledge of ways to integrate technology into English as a Foreign Language (EFL) lessons, teachers may not achieve sustainable improvement in their Computer Assisted Language Learning (CALL) professional ...
Hui-Chin Yeh, Sheng-Shiang Tseng
doaj  

Pengembangan Computer-Assisted Instruction (CAI) Untuk Pelajaran Elektronika [PDF]

, 1995
Penelitian ini bertujuan untuk mengembangkan suatu program pengajaran berbantuan komputer atau computerassisted instruction (CAI) dengan mengunakan Authoring Language (Bahasa Pembuatan) ABC dalam pelajaran elektronika dan untuk mengevaluasi program CAI ...
Surjono, Herman Dwi
core  

Computer-Assisted Instruction in Teaching Philippine Folk Dance

, 2021
Lorie A. Kloda
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Use of Computer Facilities to Develop Students English in Petaling and Hulu Langat Secondary Schools [PDF]

, 1988
Malaysian schools are encouraged to acquire computers, and use then to teach English. However, most teachers have not been trained to do this, so computer-assisted instruction may not be taking place.
Drabble, Gwynneth
core  

Computer assisted instruction comes of age in a public school system [PDF]

, 1974
William M. Richardson
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Analyzing the effects of computer-assisted dynamic assessment on L2 writing tasks for Chinese learners

Cogent Education
This study investigates the effects of computer-assisted Interventionist Dynamic Assessment (IDA) and Hybrid Dynamic Assessment (HDA) on the organizational skills of L2 writing among Chinese university students, addressing gaps in traditional product ...
Sun Wei, Yousun Shin
doaj   +1 more source

CHANGING LEARNING ENVIRONMENT THROUGH TECHNOLOGY [PDF]

Evolution of E-learning phenomenon exceeded all expectations in recent years.As a result of development of IT&C technologies and, on the other hand, due to support decision-makers at European level, the assimilation of virtual learning platforms in ...
Aleca Ofelia, Mihai Florin, Stanciu Andrei   +2 more
core