Results 31 to 40 of about 8,289,645 (254)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Culture and computer-mediated communication: Toward new understandings [PDF]

, 2005
This collection of articles was originally inspired by several presentations at CATaC'041 and subsequent critical discussion of their use of the frameworks for cultural analyses developed by Edward T. Hall (1966, 1976) and Gert Hofstede (e.g., 1980, 1991)
Ess, C., Sudweeks, F., Fay Sudweeks, Charles Ess   +3 more
core  

Bluetooth friendly names: bringing classic HCI questions into the mobile space [PDF]

, 2007
We explore the use of Bluetooth friendly names within the mobile space. Each Bluetooth-enabled device possesses a short string known as a 'friendly name' used to help identify a device to human users.
Gareth J.F. Jones, Barry Lavelle, Byrne, Daragh, Smeaton, Alan F., Lavelle, Barry, Jones, Gareth J.F., Alan F. Smeaton, Daragh Byrne   +7 more
core   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Deception in Computer-Mediated Communication [PDF]

, 2021
Computer-mediated communication on distance learning brings various effects on thelecturers and the higher-education students. Distance learning has been performed on campusesin Indonesia since the pandemic of Covid-19. This research aims to describe the
Rustanta, Agustinus, Misnawati, Desy, Misnawati, D. (Desy), Rustanta, A. (Agustinus)   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Implementation of Computer-Mediated Communication [PDF]

, 2009
This paper reports on the use of Multiply.com, a social network service (SNS) on the Internet, as a computer-mediated communication (CMC) tool for pedagogical purposes in ‘English as a Foreign Language’(EFL) classes.
ELLISON, Tina M., JEWEL, Gabriel, 246, 247, 248, COLLINS, Kim S.   +5 more
core  

Developing cross‐cultural communicative competence via computer‐assisted language learning: The case of pre‐service ESL/EFL teachers [PDF]

, 2001
Based on a qualitative research project, this article presents a view on the use of computer technology to develop a critical cross‐cultural communicative competence in English as a Second Language (ESL) / English as a Foreign Language (EFL) for pre ...
Abdelilah Salim Sehlaoui, Sehlaoui, Abdelilah   +1 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source