Results 31 to 40 of about 439,124 (294)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Evaluating Critical Thinking in Computer Mediated Communication Discussions [PDF]
Asian Journal of University Education, 2008 This paper presents an investigation of whether computer mediated communication (CMC) can develop critical thinking in language classrooms. The research was conducted at a university branch campus in Malaysia over a period of 12 weeks.
Faizah Mohamad
doaj
Computer-Mediated-Communication and Foreign Language Education
Je-LKS: Journal of E-Learning and Knowledge Society, 2012 Since the early 1990s, the increasing availability of the computer and the advent of the Internet have led to a new form of communication which helps overcome the limits of time and space, namely that which researchers and scholars refer to as Computer ...
Marta Guarda
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
ANTHROPOCENTRE OF COMPUTER MEDIATED COMMUNICATION (based on English chat sessions)
Записки з романо-германської філології, 2020 The article deals with the pragmalinguistic research of English internet relay chat as a type of mass computer mediated communication in which disembodied distant interlocutors exchange text messages online.
Н. В. Реконвальд
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Social Intelligence Design in Ambient Intelligence [PDF]
, 2009 This Special Issue of AI and Society contains a selection of papers presented at the 6th Social Intelligence Design Workshop held at ITC-irst, Povo (Trento, Italy) in July 2007.
Nijholt, A. +2 more
core +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Computer Mediated Communication
, 1992 © 1992 California Institute of Technology. Submitted August 19, 1992. I would like to express my gratitude towards NCR Corporation for its generous personal support during the final research. I am particularly indebted to Mike Graf and Tom Kunz for their constant help and unfaltering friendship.
openaire +2 more sources