Results 41 to 50 of about 8,289,645 (254)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Is it sustainable? A comparison of student and tutor online time across three distance‐learning courses [PDF]
, 1998 Distance‐learning course providers world‐wide are looking to new technology to enhance their course presentations. One of the areas they are beginning to assess is that of integrating Computer Mediated Communication (CMC) into their courses. An important
Wilson, Tina +3 more
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
'For she who knows who she is': Managing accountability in online forum messages
, 2005 The recent application of Conversation Analysis (CA) to online forum communication has been successful in explicating the sequential ties among messages.
Ardèvol Piera, Elisenda +3 more
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Computer Mediated Communication: Disseminating Information [PDF]
, 2013 Social science and humanities view computermediated communication (CMC) as a hub for information dissemination. The development and diffusion of CMC can be divided into three phases: pre-Internet CMC (beginning in the 1980), Internet-focused CMC (roughly
Anis Pervez
core
Editor’s note : JCMC in an exciting new era
, 2018 This issue of the Journal of Computer-Mediated Communication (JCMC) marks several transitions. As we start the 23rd year of the journal, and its 15th year as an journal of the International Communication Association (ICA), it is clear that JCMC has ...
Rich Ling, Ling, Richard Seyler
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source