Results 61 to 70 of about 8,289,645 (254)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
The impact of language variety and expertise on perceptions of online political discussions
, 2007 An experimental design was employed in the investigation of the impact of two status cues, language style and source expertise, on people’s perceptions of online political discussants and their intentions and motivations to participate in local online ...
Tan, Kenny W. P. +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Computer Mediated Learning: Applying Burke's Pentad
, 2008 This chapter proposes that Burke's (1969) dramatistic analysis using the Pentad (Act, Scene, Agent, Agency, Purpose) is a valuable methodological tool for investigating how learning theory offers a better understanding of mediated learning environments.
Ruth, Alison
core
Trust formation in global, virtual partnerships : Russia and the United States examined [PDF]
, 2004 Thesis Chair: Dr. Susan Wildermuth. This file was last viewed in Adobe Reader 7.0This study looks at trust formation within intercultural, virtual partnerships and how, or if, trust formation is different when all communication takes place via the ...
Sobrofski, Sara
core
A framework to analyze argumentative knowledge construction in computer-supported collaborative learning [PDF]
, 2006 Computer-supported collaborative learning (CSCL) is often based on written argumentative discourse of learners, who discuss their perspectives on a problem with the goal to acquire knowledge.
Weinberger, Armin, Fischer, Frank
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Bilingual newsgroups in Catalonia: a challenge for machine translation [PDF]
, 2003 This paper presents a linguistic analysis of a corpus of messages written in Catalan and Spanish, which come from several informal newsgroups on the Universitat Oberta de Catalunya (Open University of Catalonia; henceforth, UOC) Virtual Campus.
Taulé Delor, Mariona +6 more
core +1 more source