Results 131 to 140 of about 607,220 (287)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

齿轮类零件参数化设计系统的研究与开发

open access: yesJixie chuandong, 2009
Realizes automation which the gear class components design calculation and draws a chart, proposed take the parametrization design concept as the basis, uses which in AutoCAD inlays Visual LISP language and The DCL dialog box design language, realized ...
王鸿钧, 苏艳萍
doaj  

Facilitating laboratory automation using a robot with a simple and inexpensive camera detection system

open access: yesScientific Reports
Laboratory automation has transformed bioanalytical research, yet smaller research laboratories face challenges in adopting such technologies due to limited resources, time, and technical expertise, while already facing complex bioanalytical methods.
Rebecca Wienbruch   +6 more
doaj   +1 more source

Time Management in Wireless Sensor Networks for Industrial Process Control

open access: yesAlgorithms
This paper addresses the critical challenge of time management in wireless sensor networks (WSNs) applied to industrial process control. Although wireless technologies have gained ground in industrial monitoring, their adoption in control applications ...
Andrei Rusu   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

CAESAR: Computer Automated Resummations

open access: yes, 2004
4 pages; talk presented at DIS 2004, Strbske Pleso, Slovakia, April ...
openaire   +3 more sources

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +8 more
wiley   +1 more source

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg   +26 more
wiley   +1 more source

Rational physical agent reasoning beyond logic

open access: yes, 2009
The paper addresses the problem of defining a theoretical physical agent framework that satisfies practical requirements of programmability by non-programmer engineers and at the same time permitting fast realtime operation of agents on digital computer ...
Lincoln, Nick K., Veres, Sandor M.
core  

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