Results 91 to 100 of about 1,878,180 (248)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Beden Eğitimi Ve Spor Bölümü Öğrencilerinin Bilgisayar Kullanma Yeterlilikleri

Akademik İncelemeler Dergisi, 2014
Bu çalışmanın amacı, Beden Eğitimi ve Spor Öğretmeni adaylarının günümüzün en önemli teknolojilerinden olan bilgisayar kullanım seviyelerini ortaya koymak ve çeşitli kriterlere göre farklılıkların olup olmadığının araştırılmasıdır.Araştırmada veriler ...
Çetin Yaman, Metin Yaman
doaj  

Gender Differences in the Association Between Screen Time and Depression

AJPM Focus
Introduction: Previous research has shown that screen time is associated with depression, especially in children. Some evidence further suggests that the association may be stronger in women than in men, although findings are inconclusive.
Lauren E. Kleidermacher, MSc, Mark Olfson, MD, MPH   +1 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Dreptul la protecţia datelor cu caracter personal: esenţă şi conţinut [PDF]

Revista Institutului Naţional de Justiţie, 2014
The data protection right: essence and content Starting from the idea to prevent the apparition and development of confusion in use and in interpretation of data protection norms, by this article, we proposed to establish the limits of data ...
Mocanu Veronica
doaj  

Computational Neuroscience [PDF]

Computational and Mathematical Methods in Medicine, 2014
Jinde Cao, Qingshan Liu, Sabri Arik, Jianlong Qiu, Haijun Jiang, Ahmed Elaiw   +5 more
openaire   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source