Results 221 to 230 of about 4,540,088 (286)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nursing Informatics Competence and Digital Health Readiness Among Chinese Undergraduate Nursing Students: A Convergent Mixed-Methods Study. [PDF]

Nurs Rep
Lv Y, Li M, Yue Y, Hallensleben C, Dai H, Shen H.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Perioperative management for invasive brain-computer interface implantation under surgical navigation in a patient with traumatic spinal cord injury: a case report. [PDF]

Front Hum Neurosci
Yang S, Sun Q, Mo H, Cui W.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Automation of Monitoring Compliance with Technological Regulations Using the Example of the Process of Filling Petroleum Products. [PDF]

J Imaging
Sidorov A, Zaripov A, Tikshaev I, Pozdyshev V.   +3 more
europepmc   +1 more source

From Computer-Assisted Surgery to Extended Reality: Research Trends, Global Collaboration, and Future Directions in Craniomaxillofacial Surgery. [PDF]

Craniomaxillofac Trauma Reconstr
Sharma N, Kempter S, Oteiza JZ, Thieringer FM.   +3 more
europepmc   +1 more source

Artificial Intelligence-Assisted Colonoscopy for Colorectal Lesion Detection: Current Evidence, Challenges, and Future Directions. [PDF]

J Clin Med
Antzoulas A, Mulita F, Leivaditis V, Liolis E, Dimopoulos P, Tzelepi V, Maroulis I, Anagnostopoulos CN.   +7 more
europepmc   +1 more source

Editorial: AI-driven advances in immunology and immune-mediated disorders. [PDF]

Front Immunol
Pizzagalli DU, Porta G, Wortel IMN.
europepmc   +1 more source

Using computer games to explore foraging-predation trade-offs and spatial learning in humans. [PDF]

R Soc Open Sci
Subach S, Dorfman A, Bar A, Potudin T, Subach A, Scharf I.   +5 more
europepmc   +1 more source