Results 31 to 40 of about 45,251 (264)

Analyzing positional accuracy and structural efficiency in additive manufacturing systems with moving elements

Results in Engineering
Simulation is a useful tool for designing and analyzing the characteristics of a system being investigated. In this investigation, modal simulation and harmonic response analysis are performed to predict the dynamic characteristics of an additive ...
Tzu-Chi Chan, Sai Vijay Medarametla, Ratnakar behera   +2 more
doaj   +1 more source

R-tree data structure implementation for Computer Aided Engineering (CAE) tools

International Journal for Simulation and Multidisciplinary Design Optimization, 2021
Searching and handling geometric data are basic requirements of any Computer Aided Engineering application (CAE). Spatial search and local search has greater importance in CAD and CAE applications for reducing the model preparation time.
Shelar Vaibhav, Subramani Selamani, Davidson Jebaseelan   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Spatiotemporal Trajectories of Pedestrian Mobility at the Train Station: evidence of 24 million trajectories

Scientific Data
Understanding pedestrian movement remains crucial for designing efficient and safe transportation structures such as terminals, stations, or airports. The significance of conducting a granular analysis in pedestrian mobility dynamics research is evident ...
Tomáš Apeltauer, Ondřej Uhlík, Jiří Apeltauer, Vojtěch Juřík   +3 more
doaj   +1 more source

Microlens Array Fabrication by Using a Microshaper

Micromachines, 2021
A simple, easy, inexpensive, and quick nonsilicon-based micromachining method was developed to manufacture a microlens array. The spherical surface of the microlens was machined using a microshaper mounted on a three-axis vertical computer numerical ...
Meng-Ju Lin, Cheng Hao Wen
doaj   +1 more source

Computer-Aided Reverse Engineering of Protected Software

, 2023
Reverse engineering is undoing or circumventing the protections deployed on a code region. Software crackers perform this to remove license checks in commercial applications and video games, but it can also be done for legitimate purposes. Many software houses perform a security assessment phase by reverse engineering their protected software before ...
Daniele Canavese, Leonardo Regano, Antonio Lioy   +2 more
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source