Results 51 to 60 of about 21,987 (211)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

30th Symposium on Computer Aided Process Engineering

, 2020
30th European Symposium on Computer Aided Chemical Engineering, Volume 47 contains the papers presented at the 30th European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Milan, Italy, May 24-27, 2020.
Various Authors, Bozzano, Giulia, Pierucci, Sauro, Manca, Davide, Manenti, Flavio   +4 more
core  

12th CIRP Conference on Computer Aided Tolerancing [PDF]

, 2011
The purpose of this paper is to decipher the process of modelling driving to the product behaviour simulation. A simple example of simulation, tolerance stackup, allows illustrating this process.
BALLU, Alex, PAILHES, Jerome, CHARPENTIER, Frédéric   +2 more
core  

A two-stage multi-scale attention-based network for weakly supervised cataract fundus image enhancement

Scientific Reports
Cataract is a major cause of vision loss and hinders further diagnosis. However, enhancing cataract fundus images remains challenging due to limited paired cataract retinal images and the difficulty of recovering fine details in the retinal images.
Xiaoyong Fang, Yue Wang, Xiangyu Li, Wanshu Fan, Dongsheng Zhou   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Computer‐based laboratory simulation: Evaluations of student perceptions [PDF]

, 1996
Providing resources to meet the needs of oil workers who miss blocks of an engineering course was the motivation for producing computer‐based simulations of laboratory equipment. This paper reports on student perceptions of various aspects of the package.
Edward, Norrie, Norrie S. Edward
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Genuine lab experiences for students in resource constrained environments: The RealLab with integrated intelligent assessment. [PDF]

, 2008
Laboratory activities are indispensable for developing engineering skills. Computer Aided Learning (CAL) tools can be used to enhance laboratory learning in various ways, the latest approach being the virtual laboratory technique that emulates ...
Chika, I., Azzi, Djamel, Chika, Ifeyinwa Eucharia, Stocker, J., Haynes, B., Stocker, James, Achumba, Ifeyinwa, Haynes, Barry P.   +7 more
core  

A Metamodel for the Rubus Component Model: Extensions for Timing and Model Transformation From EAST-ADL

IEEE Access, 2017
According to the model-driven engineering paradigm, one of the entry requirements when realizing a seamless tool chain for the development of software is the definition of metamodels, to regulate the specification of models, and model transformations ...
Alessio Bucaioni, Antonio Cicchetti, Federico Ciccozzi, Saad Mubeen, Mikael Sjodin   +4 more
doaj   +1 more source