Results 101 to 110 of about 926,629 (301)

Optical polarization imaging for underwater target detection with non-scatter background

open access: yesJournal of Measurement Science and Instrumentation, 2020
For conventional optical polarization imaging of underwater target, the polarization degree of backscatter should be pre-measured by averaging the pixel intensities in the no target region of the polarization images, and the polarization property of the ...
GUAN Jin-ge   +10 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

PEMAHAMAN TEORI DATA WAREHOUSE BAGI MAHASISWA TAHUN AWAL JENJANG STRATA SATU BIDANG ILMU KOMPUTER

open access: yesJurnal Informatika, 2015
As a Computer scientist, a computer science students should have understanding about database theory as a concept of data maintenance. Database will be needed in every single human real life computer implementation such as information systems ...
Harco Leslie Hendric Spits Warnars   +2 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Role, Methodology, and Measurement of Cognitive Load in Computer Science and Information Systems Research

open access: yesIEEE Access
Cognitive load (CL), defined as the mental effort required to process information, plays a pivotal role in user performance and experience in various domains, particularly within computer science (CS) and information systems (IS).
Mira Suryani   +7 more
doaj   +1 more source

An Effective Modality Conflict Model for Identifying Applicable Policies During Policy Evaluation [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2018
Policy evaluation is a process to determine whether a request submitted by a user satisfies the access control policies defined by an organization. Modality conflict is one of the main issues in policy evaluation.
Hamidah Ibrahim   +3 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

METHODICAL ASPECTS OF SYSTEM MAXIMA IN LEARNING PROCESS OF OPERATIONS RESEARCH

open access: yesÌнформаційні технології в освіті, 2016
Training of operations research of bachelors of Computer Science is particularly important because combines both fundamental concepts and principles of mathematics and informational different disciplines and applied models and algorithms for their use ...
Taras Kobylnyk, Ulyana Kogut
doaj  

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