Results 101 to 110 of about 926,629 (301)
Optical polarization imaging for underwater target detection with non-scatter background
For conventional optical polarization imaging of underwater target, the polarization degree of backscatter should be pre-measured by averaging the pixel intensities in the no target region of the polarization images, and the polarization property of the ...
GUAN Jin-ge +10 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
PEMAHAMAN TEORI DATA WAREHOUSE BAGI MAHASISWA TAHUN AWAL JENJANG STRATA SATU BIDANG ILMU KOMPUTER
As a Computer scientist, a computer science students should have understanding about database theory as a concept of data maintenance. Database will be needed in every single human real life computer implementation such as information systems ...
Harco Leslie Hendric Spits Warnars +2 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Cognitive load (CL), defined as the mental effort required to process information, plays a pivotal role in user performance and experience in various domains, particularly within computer science (CS) and information systems (IS).
Mira Suryani +7 more
doaj +1 more source
An Effective Modality Conflict Model for Identifying Applicable Policies During Policy Evaluation [PDF]
Policy evaluation is a process to determine whether a request submitted by a user satisfies the access control policies defined by an organization. Modality conflict is one of the main issues in policy evaluation.
Hamidah Ibrahim +3 more
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
METHODICAL ASPECTS OF SYSTEM MAXIMA IN LEARNING PROCESS OF OPERATIONS RESEARCH
Training of operations research of bachelors of Computer Science is particularly important because combines both fundamental concepts and principles of mathematics and informational different disciplines and applied models and algorithms for their use ...
Taras Kobylnyk, Ulyana Kogut
doaj

