Results 71 to 80 of about 770,880 (300)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A bibliometric overview of the Journal of Network and Computer Applications between 1997 and 2019

open access: yes, 2020
© 2020 Elsevier Ltd A bibliometric analysis of the Journal of Network and Computer Applications (JNCA) for the 1997–2019 period is performed. This analysis uncovers the structural and hidden implications of this journal.
Merigó, JM   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Computer system dependability : an introduction [PDF]

open access: yes
More reliance is being placed on computer systems in many applications. Such systems need to be dependable; we must be able to depend on them to provide the required level of service without failure.
Lord, Andrew M.
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Artificial Intelligence Applications for Brain–Computer Interfaces

open access: yes
Artificial Intelligence Applications for Brain-Computer Interfaces focuses on the advancements, challenges, and prospects of future technologies involving noninvasive brain-computer interfaces (BCIs). It includes the processing and analysis of multimodal
Subasi, Abdulhamit   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Digital Competence Learning Ecosystem in Higher Education: A Mapping and Systematic Review of the Literature

open access: yesIEEE Access
The digital competences of university students are developed using a digital learning ecosystem that integrates: 1) virtual learning environments; 2) digital learning tools; and 3) learning methodologies.
Maylin Suleny Bojorquez-Roque   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A MAGIQ-TOPSIS-Fuzzy-Logic Based Cloud Service Providers Ranking Model for Federated Cloud Computing Environment

open access: yesAdvances in Electrical and Computer Engineering
In the era of multi-cloud environments, the challenge for end users or organizations is to select the most appropriate cloud service provider (CSP) due to the complexity and variability of service-level offerings by various CSPs.
SARAF, V., ADHAO, R., PACHGHARE, V.
doaj   +1 more source

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