Results 71 to 80 of about 5,552,920 (364)

Computer Analysis of Architecture Using Automatic Image Understanding

, 2019
In the past few years, computer vision and pattern recognition systems have been becoming increasingly more powerful, expanding the range of automatic tasks enabled by machine vision.
Li, Yuan, Shamir, Lior, Wei, Fan
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Techniques for improving reliability of computers [PDF]

, 1972
Modular design techniques improve methods of error detection, diagnosis, and recovery. Theoretical computer (MARCS (Modular Architecture for Reliable Computer Systems)) study deals with postulated and modeled technology indigenous to 1975-1980.
Bouricius, W. G., Cater, W. C., Jessep, D. C., Mccarthy, C. E., Milligan, F. G., Wadia, A. B.   +5 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

RASP ABSTRACT MACHINE EMULATOR – EXTENDING THE EMUSTUDIO PLATFORM [PDF]

Acta Electrotechnica et Informatica, 2017
This paper presents the RASP (Random Access Stored Program) abstract machine emulator implemented as a plugin for emuStudio – extendable platform for computer architectures emulation.
Michal ŠIPOŠ, Slavomír ŠIMOŇÁK
doaj   +1 more source

BRISC-V emulator: a standalone, installation-free, browser-based teaching tool [PDF]

, 2020
Many computer organization and computer architecture classes have recently started adopting the RISC-V architecture as an alternative to proprietary RISC ISAs and architectures.
Isakov, Mihailo, Kinsy, Michel A.
core  

Continuum computer architecture for exaflops computation [PDF]

Communications of the ACM, 2001
The ultimate computers in our long-term future will deliver exaflops-scale performance (or greater) and will look very different from today’s micro-processors and massively parallel computers. Ironically, however, their alien structures and operational behavior can be inferred from the same technology trends driving development of today’s conventional
openaire   +4 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Supporting Constructive Learning with a Feedback Planner [PDF]

, 2000
A promising approach to constructing more effective computer tutors is implementing tutorial strategies that extend over multiple turns. This means that computer tutors must deal with (1) failure, (2) interruptions, (3) the need to revise their tactics ...
Core, Mark G., Moore, Johanna, Zinn, Claus   +2 more
core   +2 more sources

Array languages and the challenges of modern computer architecture [PDF]

, 2004
There has always been a close relationship between programming language design and computer design. Electronic computers and programming languages are both 'computers' in Turing's sense.
Blelloch G., Paul Cockshott
core   +1 more source