Results 21 to 30 of about 28,205 (240)
Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]
Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
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Updates in metabolomics tools and resources: 2014-2015 [PDF]
Data processing and interpretation represent the most challenging and time-consuming steps in high-throughput metabolomic experiments, regardless of the analytical platforms (MS or NMR spectroscopy based) used for data acquisition.
Misra, Biswapriya B. +1 more
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Bottom-up construction of ontologies [PDF]
Presents a particular way of building ontologies that proceeds in a bottom-up fashion. Concepts are defined in a way that mirrors the way their instances are composed out of smaller objects.
Mars, N.J.I., Vet, P.E. van der
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Development of a system for computer-assisted structure elucidation of small organic compounds [PDF]
An unambiguous interpretation and evaluation of nuclear magnetic resonance (NMR) data for the elucidation of chemical structures can become a challenge for organic or natural product chemists.
Wenk, Michael
core
Indonesian tropical soft corals are valuable resources that produce pharmacological cytotoxic cembranoids. However, the manual structure determination in these compounds requires adequate knowledge of organic chemistry.
Hedi Indra Januar +3 more
doaj +1 more source
Differentiating signals to make biological sense – a guide through databases for MS-based non-targeted metabolomics [PDF]
Metabolite identification is one of the most challenging steps in metabolomics studies and reflects one of the greatest bottlenecks in the entire workflow.
Armitage, Emily Grace +4 more
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Background Current efforts in Metabolomics, such as the Human Metabolome Project, collect structures of biological metabolites as well as data for their characterisation, such as spectra for identification of substances and measurements of their ...
Neumann Steffen +3 more
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Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism. [PDF]
The human histamine H4 receptor (hH4R), a member of the G-protein coupled receptors (GPCR) family, is an increasingly attractive drug target. It plays a key role in many cell pathways and many hH4R ligands are studied for the treatment of several ...
Matteo Pappalardo +7 more
doaj +1 more source
Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]
We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M. +3 more
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Structure analysis of biologically important prokaryotic glycopolymers [PDF]
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria +1 more
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