Results 81 to 90 of about 286,457 (305)

Examining outcomes for service users accessing the Breaking Free Online computer-assisted therapy program for substance use disorders via a 'telehealth' approach: protocol for a two arm, parallel group randomized controlled trial. [PDF]

Addict Sci Clin Pract, 2023
Elison-Davies S, Pittard L, Myton T, Jones A, Ward J, Davies G.   +5 more
europepmc   +1 more source

Focal Spot, Winter 1972 [PDF]

, 1972
https://digitalcommons.wustl.edu/focal_spot_archives/1004/thumbnail ...

core   +1 more source

Beyond cute: exploring user types and design opportunities of virtual reality pet games [PDF]

, 2017
Virtual pet games, such as handheld games like Tamagotchi or video games like Petz, provide players with artificial pet companions or entertaining pet-raising simulations. Prior research has found that virtual pets have the potential to promote learning,
Brady, Erin, Dombrowski, Lynn, Faas, Travis, Lin, Chaolan   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Brain–computer interface and assist-as-needed model for upper limb robotic arm

Advances in Mechanical Engineering, 2019
Post-stroke paralysis, whereby subjects loose voluntary control over muscle actuation, is one of the main causes of disability. Repetitive physical therapy can reinstate lost motions and strengths through neuroplasticity.
Akim Kapsalyamov, Shahid Hussain, Askhat Sharipov, Prashant Jamwal   +3 more
doaj   +1 more source

Initial findings from a mixed-methods evaluation of computer-assisted therapy for substance misuse in prisoners: Development, implementation and clinical outcomes from the ‘Breaking Free Health & Justice’ treatment and recovery programme

Frontiers in Public Health, 2015
Background: Within the United Kingdom’s ‘Transforming Rehabilitation’ agenda, reshaping drug and alcohol interventions in prisons is central to the Government’s approach to addressing substance dependence in the prison population and reduce reoffending ...
Sarah Elison, Samantha Weston
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Medical image computing and computer-aided medical interventions applied to soft tissues. Work in progress in urology

, 2006
Until recently, Computer-Aided Medical Interventions (CAMI) and Medical Robotics have focused on rigid and non deformable anatomical structures. Nowadays, special attention is paid to soft tissues, raising complex issues due to their mobility and ...
Bart, Stéphane, Baumann, Michael, Berkelman, Peter, Bolla, Michel, Chartier-Kastler, Emmanuel, Cinquin, Philippe, Daanen, Vincent, Descotes, Jean-Luc, Dusserre, Andrée, Giraud, Jean-Yves, Leroy, Antoine, Long, Jean-Alexandre, Marchal, Maud, Moalic, Ronan, Mozer, Pierre, Payan, Yohan, Promayon, Emmanuel, Troccaz, Jocelyne, Voros, Sandrine   +18 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Optic and motor alteration in Balint syndrome: computer assisted occupational therapy

European Journal of Human Movement, 2010
Balint Syndrome, which was reported in 1909, is an affection produced by bilateral parieto-occipital lesions affecting the connections between the visual cortical regions and the prerolandic motor areas and caracterized by visual ataxia, failure to grasp
L.P. Rodríguez, R. Moreno, C. Flórez
doaj