From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Examining outcomes for service users accessing the Breaking Free Online computer-assisted therapy program for substance use disorders via a 'telehealth' approach: protocol for a two arm, parallel group randomized controlled trial. [PDF]
Addict Sci Clin Pract, 2023 Elison-Davies S +5 more
europepmc +1 more source
DiagnosticsBackground/Objectives: Establishing laparoscopic access remains a critical and complication-prone step in minimally invasive surgery. Previous work has shown that proximal vibroacoustic sensing can identify peritoneal puncture events in porcine cadavers.
Moritz Spiller +6 more
doaj +1 more source
A critical look at the validity of studies that focus on humans versus machines teaching grammer [PDF]
, 2002 Plan BAlmost from birth, the procession to learning language begins from responding to noises in the environment to learning new information throughout the lifespan. Yet, not every child learns how to speak properly.
Stang, Patricia A.
core
, 2016 BACKGROUND: Manual therapy (MT) and exercise have been extensively used to treat people with musculoskeletal conditions such as temporomandibular disorders (TMD). The evidence regarding their effectiveness provided by early systematic reviews is outdated.
Neto, Francisco +7 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Monitor Unit Verification for Radiotherapy Irregular Fields Based On the Clarkson Method Combined With In-House MLC Shaper Software [PDF]
Iranian Journal of Medical PhysicsIntroduction: In the present scenario, high precision-radiotherapy is delivered through Linear accelerators in which the dose delivery is achieved by delivering the proper monitor unit (MU).
Athiyaman M +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optic and motor alteration in Balint syndrome: computer assisted occupational therapy
European Journal of Human Movement, 2010 Balint Syndrome, which was reported in 1909, is an affection produced by bilateral parieto-occipital lesions affecting the connections between the visual cortical regions and the prerolandic motor areas and caracterized by visual ataxia, failure to grasp
L.P. Rodríguez, R. Moreno, C. Flórez
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source