Results 121 to 130 of about 3,425,301 (304)
Bulletin of "Carol I" National Defense UniversityThis article presents a study on moral codes and professional codes of conduct. Various professional codes of conduct were considered, including the Samurai Code of Conduct, Code of Chivalry, Pirate Code, Hippocratic Oath and Medical Oath, Red Cross Code
Elitsa PETROVA
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Slow Impacts on Strong Targets Bring on the Heat
Geophysical Research Letters, 2018 An important new paper by Kurosawa and Genda (2017, https://doi.org/10.1002/2017GL076285) reports a previously overlooked source of heating in low velocity meteorite impacts.
H. J. Melosh, B. A. Ivanov
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A parallel Viterbi decoder for block cyclic and convolution codes
, 2005 We present a parallel version of Viterbi's decoding procedure, for which we are able to demonstrate that the resultant task graph has restricted complexity in that the number of communications to or from any processor cannot exceed 4 for BCH codes.
Amarasinghe, Kosala +3 more
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Calibration and prediction of two nested computer codes
, 2017 Thanks to computing power increase, risk quantification relies more and more on computer modeling. Methods of risk quantification based on a fixed computational budget exist, but computer codes are almost always considered as a single black box.
Perrin, Guillaume +2 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
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Computer codes for thermal design of potassium boilers and condensers [PDF]
, 1966 Computer codes for thermal design of multiple tube potassium condensers and ...
Ferguson, D. R.
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2004 We propose a generic algorithm for the construction of efficient reversible variable-length codes (RVLCs) and variable-length error-correcting (VLEC) codes, which optimizes the codeword length distribution.
Wang, J., Yang, L-L., Hanzo, L.
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