Results 131 to 140 of about 3,425,301 (304)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Linear Codes for Hyperdimensional Computing
Neural ComputationAbstract Hyperdimensional computing (HDC) is an emerging computational paradigm for representing compositional information as high-dimensional vectors and has a promising potential in applications ranging from machine learning to neuromorphic computing.
openaire +5 more sources
, 2006 LT-codes are a new class of codes introduced by Luby for the purpose of scalable and fault-tolerant distribution of data over computer networks. In this paper, we introduce Raptor codes, an extension of LT-codes with linear time encoding and decoding. We
Shokrollahi, Amin, Amin Shokrollahi
core +1 more source
, 2006 The novel family of redundant residue number system (RRNS) codes is studied. RRNS codes constitute maximum–minimum distance block codes, exhibiting identical distance properties to Reed–Solomon codes.
Liew, T.H., Yang, L-L., Hanzo, L.
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Whistleblowing: an ethical dilemma
Российские биомедицинские исследования, 2016 Because most organizations depend on computer systems that electronically store important data to perform crucial business functions, the integrity of these information systems is paramount. Securing company systems, however, is not always an easy task.
Raj Yagna
doaj +2 more sources
Analysis for Gaussian Approximation and Structure Optimization of IRA Codes
工程科学与技术, 2007 :Code structure is an important factor which affects performance of IRA codes. THe structure of IRA codes was optimized based on Gaussian approximation. The graph model theory of IRA codes was introduced, and the Tanner graph was presented. The impact of
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source