Results 121 to 130 of about 1,170,289 (309)
Laser beam modeling in optical storage systems [PDF]
A computer model has been developed that simulates light propagating through an optical data storage system. A model of a laser beam that originates at a laser diode, propagates through an optical system, interacts with a optical disk, reflects back from
Flagello, D. G. +2 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Virtual computers and virtual data storage
, 2013 Virtual data storage represents a new business model which includes various concepts such as virtualization, design of distributed applications and management which enables flexible data access. These methods include using networks of remote servers instead of local servers and personal computers for storing, managing and editing data.
Šimec, Alen, Staničić, Ognjen
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Decimal to Binary Number Conversion can be Fun [PDF]
Numbering systems are of great importance in Computer Science and Engineering education. The binary numbering system can be considered as one of the most fundamental, since its understanding is essential for the understanding of other Computer Science ...
Polycarpou, Irene
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Computer-based communication in support of scientific and technical work [PDF]
Results are reported of the first experiments for a computer conference management information system at the National Aeronautics and Space Administration.
Vallee, J., Wilson, T.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Beginner's Guide for Cybercrime Investigators [PDF]
, 2014 In the real world there are people who enter the homes and steal everything they find valuable. In the virtual world there are individuals who penetrate computer systems and "steal" all your valuable data.
Sfetcu, Nicolae
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source