Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli. [PDF]
, 2016 A significant obstacle in training predictive cell models is the lack of integrated data sources. We develop semi-supervised normalization pipelines and perform experimental characterization (growth, transcriptional, proteome) to create Ecomics, a ...
Kim, Minseung +3 more
core +2 more sources
Combined sequence and copy number analysis improves diagnosis of limb girdle and other myopathies
Annals of Clinical and Translational Neurology, 2023 Objective Clinical and genetic heterogeneities make diagnosis of limb‐girdle muscular dystrophy (LGMD) and other overlapping disorders of muscle weakness complicated and expensive.
Babi R. R. Nallamilli +8 more
doaj +1 more source
Criteria for the use of omics-based predictors in clinical trials. [PDF]
, 2013 The US National Cancer Institute (NCI), in collaboration with scientists representing multiple areas of expertise relevant to 'omics'-based test development, has developed a checklist of criteria that can be used to determine the readiness of omics-based
A Dupuy +25 more
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The Personal Genome Project-UK, an open access resource of human multi-omics data [PDF]
, 2019 Integrative analysis of multi-omics data is a powerful approach for gaining functional insights into biological and medical processes. Conducting these multifaceted analyses on human samples is often complicated by the fact that the raw sequencing output
Beck, Stephan +12 more
core +2 more sources
Inferring gene ontologies from pairwise similarity data. [PDF]
, 2014 MotivationWhile the manually curated Gene Ontology (GO) is widely used, inferring a GO directly from -omics data is a compelling new problem. Recognizing that ontologies are a directed acyclic graph (DAG) of terms and hierarchical relations, algorithms ...
Bafna, Vineet +4 more
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Machine Learning and Integrative Analysis of Biomedical Big Data. [PDF]
, 2019 Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome)
Choi, Howard +5 more
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2D association and integrative omics analysis in rice provides systems biology view in trait analysis. [PDF]
, 2018 The interactions among genes and between genes and environment contribute significantly to the phenotypic variation of complex traits and may be possible explanations for missing heritability.
Dai, Xinbin +3 more
core +2 more sources
A SNP variation in an expansin (EgExp4) gene affects height in oil palm [PDF]
PeerJ, 2022 Oil palm (Elaeis guineensis Jacq.), an Aracaceae family plant, is utilized for both consumable and non-consumable products, including cooking oil, cosmetics and biodiesel production.
Suthasinee Somyong +8 more
doaj +2 more sources
Mitochondrial DNA. Part B. Resources, 2022 This study presents the first complete mitochondrial genome of the Hipposideros pendleburyi (Pendlebury's leaf-nosed bat), an endemic species in Thailand.
Wasitthee Kongkachana +7 more
doaj +1 more source
Nutrigenomics and immune function in fish : new insights from omics technologies [PDF]
, 2017 This study was funded by BBSRC grant BB/M026604/1.Peer reviewedPublisher ...
Krol, Elzbieta, Martin, Samuel A. M.
core +1 more source