Results 1 to 10 of about 14,144 (239)

Phosphoproteomics-based systems analysis of signal transduction networks

Frontiers in Physiology, 2012
Signal transduction systems coordinate complex cellular information to regulate biological events such as cell proliferation and differentiation. Although the accumulating evidence on widespread association of signaling molecules has revealed essential ...
Hiroko eKozuka-Hata, Shinya eTasaki, Masaaki eOyama   +2 more
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Proteomics and phosphoproteomics to study Tuina reverses capsule fibrosis in frozen shoulder: a research report based on rats

Scientific Reports
Frozen shoulder (FS) is a common disorder often treated with Tuina, but the mechanisms involved remain unclear. We employed proteomics and phosphoproteomics to investigate the mechanisms associated with the treatment of capsule fibrosis in FS rats.
Yingjie Qiao, Jianmin Wang, Lijun Zheng, Yanhong Yang, Huadong Li, Muzhen Li, Shidong Zhang, Hongyi Wang, Tiantian Zhang   +8 more
doaj   +1 more source

iProteinDB: An Integrative Database of Drosophila Post-translational Modifications

G3: Genes, Genomes, Genetics, 2019
Post-translational modification (PTM) serves as a regulatory mechanism for protein function, influencing their stability, interactions, activity and localization, and is critical in many signaling pathways.
Yanhui Hu, Richelle Sopko, Verena Chung, Marianna Foos, Romain A. Studer, Sean D. Landry, Daniel Liu, Leonard Rabinow, Florian Gnad, Pedro Beltrao, Norbert Perrimon   +10 more
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Comparative Ser/Thr/Tyr phosphoproteomics between two Mycobacterial species: The fast growing Mycobacterium smegmatis and the slow growing Mycobacterium bovis BCG.

Frontiers in Microbiology, 2015
Ser/Thr/Tyr protein phosphorylation plays a critical role in regulating mycobacterial growth and development. Understanding the mechanistic link between protein phosphorylation signaling network and mycobacterial growth rate requires a global view of the
Kehilwe Confidence Nakedi, Andrew JM Nel, Shaun eGarnett, Jonathan M Blackburn, Nelson Da Cruz Soares   +4 more
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Coactosin Phosphorylation Controls Entamoeba histolytica Cell Membrane Protrusions and Cell Motility

mBio, 2020
Invasion of the colon wall by Entamoeba histolytica during amoebic dysentery entails migration of trophozoites through tissue layers that are rich in extracellular matrix. Transcriptional silencing of the E.
Muhammad M. Hasan, José E. Teixeira, Ying-Wai Lam, Christopher D. Huston   +3 more
doaj   +1 more source

Sustained mitogen-activated protein kinase activation reprograms defense metabolism and phosphoprotein profile in Arabidopsis thaliana.

Frontiers in Plant Science, 2014
Mitogen-activated protein kinases (MAPKs) target a variety of protein substrates to regulate cellular signaling processes in eukaryotes. In plants, the number of identified MAPK substrates that control plant defense responses is still limited.
Ines eLassowskat, Christoph eBoettcher, Christoph eBoettcher, Lennart eEschen-Lippold, Dierk eScheel, Justin eLee   +5 more
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Multi-Omics Studies towards Novel Modulators of Influenza A Virus–Host Interaction

Viruses, 2016
Human influenza A viruses (IAVs) cause global pandemics and epidemics. These viruses evolve rapidly, making current treatment options ineffective.
Sandra Söderholm, Yu Fu, Lana Gaelings, Sergey Belanov, Laxman Yetukuri, Mikhail Berlinkov, Anton V. Cheltsov, Simon Anders, Tero Aittokallio, Tuula A. Nyman, Sampsa Matikainen, Denis E. Kainov   +11 more
doaj   +1 more source

ATR phosphoproteomics

, 2023
R scripts used in the publication for the analysis of the phospho-proteomics dataset.
Jadav, Rathan S, Weiland, Florian, Carroll, Thomas, Gao, Yuandi, Wang, Jianming, Zhou, Houjiang, Lamoliatte, Frederic, Muñoz, Ivan, Toth, Rachel, Macartney, Thomas, van Attikum, Haico, Brown, Fiona, Hastie, James, Alabert, Constance, Zenke, Frank, Noordermeer, Sylvie, Masson, Jean-Yves, Rouse, John   +17 more
openaire   +3 more sources

Quantitative phosphoproteomic analysis of chicken DF-1 cells infected with Eimeria tenella, using tandem mass tag (TMT) and parallel reaction monitoring (PRM) mass spectrometry

Parasite
Eimeria tenella is an obligate intracellular parasite which causes great harm to the poultry breeding industry. Protein phosphorylation plays a vital role in host cell–E. tenella interactions.
Jia Liu-Shu, Liu Zhan, Zhu Shun-Hai, Zhao Qi-Ping, Han Hong-Yu, Zhao Huan-Zhi, Yu Yu, Dong Hui   +7 more
doaj   +1 more source

A global view of substrate phosphorylation and dephosphorylation during budding yeast mitotic exit

Microbial Cell, 2018
The cell cycle is the process by which a cell duplicates its DNA during S-phase and divides its chromosomes during M-phase, creating two genetically identical daughter cells.
Sandra A. Touati, Frank Uhlmann
doaj   +1 more source