Results 1 to 10 of about 267,519 (299)

Proteome-Wide Structural Probing of Low-Abundant Protein Interactions by Cross-Linking Mass Spectrometry

, 2020
Proteome-wide cross-linking studies have spurred great interest as they facilitate structural probing of protein interactions in living cells and organisms. However, current studies have a bias for high-abundant proteins.
Stefan G. Kreft (8462427), Julius Fürsch (8462421), Kai-Michael Kammer (8462424), Martin Beck, Florian Stengel, Stefan G. Kreft, Martin Beck (844357), Kai-Michael Kammer, Florian Stengel (428563), Julius Fürsch   +9 more
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The evolution of the plant organellar proteome

, 2022
A hallmark of eukaryotic cells is the compartmentalisation of intracellular processes into specialised, membrane-bound compartments known as organelles. The function of organelles is dependent on a suite of proteins localised within them (the organellar ...
Costello, Rona Moira Oonagh
core   +1 more source

Facile One-Pot Nanoproteomics for Label-Free Proteome Profiling of 50–1000 Mammalian Cells [PDF]

, 2021
Recent advances in sample preparation enable label-free mass spectrometry (MS)-based proteome profiling of small numbers of mammalian cells. However, specific devices are often required to downscale sample processing volume from the standard 50-200 μL to
Shi, T, Sontag, RL, Yang, B, Orton, Daniel J, Rodland, KD, Liu, T, Martin, K, Smith, Richard D, Habowski, Amber N, Zhao, R, Waterman, ML, Sontag, Ryan L, Zhang, Tong, Rodland, Karin D, Zhao, Rui, Zhang, T, Tsai, C-F, Waterman, Marian L, Lu, Y-J, Lu, Yong-Jie, Chrisler, WB, Wiley, H Steven, Orton, DJ, Martin, Kendall, Lin, T-T, Chrisler, William B, Lin, Tai-Tu, Habowski, AN, Qian, W-J, Smith, RD, Wiley, HS, Yang, Bin, Liu, Tao, Qian, Wei-Jun, Shi, Tujin, Tsai, Chia-Feng   +35 more
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Defining the core proteome of the chloroplast envelope membranes [PDF]

, 2013
High-throughput protein localization studies require multiple strategies. Mass spectrometric analysis of defined cellular fractions is one of the complementary approaches to a diverse array of cell biological methods. In recent years, the protein content
Bernd Müller, Enrico eSchleiff, Mirus, Oliver, Stefan Simm, Michael Karas, Papasotiriou, Dimitrios, Papasotiriou, Dimitrios G., Dimitrios G. Papasotiriou, Schleiff, Enrico, Oliver Mirus, Bernd eMüller, Maik eSommer, Matthias S. Leisegang, Sommer, Maik Sascha, Maik S. Sommer, Dimitri ePapasotiriou, Stefan eSimm, Leisegang, Matthias S., Simm, Stefan, Mohamed eIbrahim, Oliver eMirus, Schorge, Tobias, Enrico Schleiff, Ibrahim, Mohamed, Matthias eLeisegang, Mohamed Ibrahim, Michael eKaras, Tobias Schorge, Müller, Bernd, Sommer, Maik S., Leisegang, Matthias, Tobias eSchorge, Karas, Michael   +32 more
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Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

, 2022
S.2072-2091Analysis of induced sputum supernatant is a minimally invasive approach to study the epithelial lining fluid and, thereby, provide insight into normal lung biology and the pathobiology of lung diseases.
Xian, Yang, Adcock, Ian M., Djukanovic, Ratko, Wilson, Susan J., Caruso, Massimo, Burg, Dominic, Sterk, Peter J., Bansal, Aruna T., Schofield, James P.R., Auffray, Charles, Ward, Jonathan A., Hashimoto, Simone, Singer, Florian, Sousa, Ana R., Fleming, Louise, Bakke, Per S., Brandsma, Joost, Pandis, Ioannis, Shaw, Dominick E., Fowler, Stephen J., Howarth, Peter, Montuschi, Paolo, Staykova, Doroteya, Skipp, Paul J., Horvath, Ildiko, Lutter, René, Krug, Norbert, Sanak, Marek, Sandström, Thomas, Folisi, Caterina, Rowe, Anthony, Nicholas, Ben, Sun, Kai, Chung, Kian F., Dahlén, Sven-Erik, Corfield, Julie   +35 more
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The yeast vacuolar membrane proteome [PDF]

, 2009
Transport of solutes between the cytosol and the vacuolar lumen is of crucial importance for various functions of vacuoles, including ion homeostasis; detoxification; storage of different molecules such as amino acids, phosphate, and calcium ions; and ...
Poolman, Bert,, Slotboom, Dirk J.,, Breitling, Rainer, Permentier, Hjalmar P.,, Gandhi, Tejas, Breitling, R., Breitling, Rainer,, Slotboom, D.J., Gandhi, Tejas,, Permentier, Hjalmar P., Permentier, H.P., Gandhi, T., Wiederhold, Elena,, Poolman, Bert, Wiederhold, Elena, Wiederhold, E., Poolman, B., Permentier, Hjalmar P.; id_orcid, Slotboom, Dirk J.   +18 more
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Assessing the contribution of alternative splicing to proteome diversity in Arabidopsis thaliana using proteomics data [PDF]

, 2011
Background Large-scale analyses of genomics and transcriptomics data have revealed that alternative splicing (AS) substantially increases the complexity of the transcriptome in higher eukaryotes.
Dijk, A.D.J., van, van Dijk Aalt DJ, Severing, E.I., Roeland CHJ van Ham, Ham, R.C.H.J., van, van Dijk, A.D.J., van Ham, R.C.H.J., Severing Edouard I, Edouard I Severing, Aalt DJ van Dijk, van Ham Roeland CHJ   +10 more
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An update on the mouse liver proteome

, 2009
Art. 35Background: Decoding of the liver proteome is subject of intense research, but hampered by methodological constraints. We recently developed an improved protocol for studying rat liver proteins based on 2-DE-MALDI-TOF-MS peptide mass finger ...
Borlak, J., Gazzana, G.
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Improved Membrane Proteomics Coverage of Human Embryonic Stem Cells by Peptide IPG-IEF

, 2009
Protein biomarkers are fundamental tools for the characterization of stem cells and for tracking their differentiation and maturation down developmental lineages.
Schmidt, Uli, Pascovici, Dana, McQuade, Leon, Baker, Mark S. S, Stojanov, Tomas   +4 more
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Proteome-Wide Deconvolution of Drug Targets and Binding Sites by Lysine Reactivity Profiling

, 2022
Recently, numerous efforts have been devoted to identifying drug targets and binding sites in complex proteomes, which is of great importance in modern drug discovery.
Mingliang Ye (19659), Kejia Li (6262511), Chengfei Ruan (8136330), Jiahua Zhou (2617603), Zheng Fang (727034), Xiaolei Zhang (316541), Zhouxian Li (10270108)   +6 more
core   +3 more sources