Results 31 to 40 of about 429,532 (300)
Toward an understanding of the protein interaction network of the human liver
Proteomeāscale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery.
Jian Wang +37 more
doaj +1 more source
Proteoforms expand the world of microproteins and short open reading frame-encoded peptides
Summary: Microproteins and short open reading frame-encoded peptides (SEPs) can, like all proteins, carry numerous posttranslational modifications. Together with posttranscriptional processes, this leads to a high number of possible distinct protein ...
Liam Cassidy +2 more
doaj +1 more source
Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. [PDF]
Small ubiquitin-like modifier (SUMO) modification regulates numerous cellular processes. Unlike ubiquitin, detection of endogenous SUMOylated proteins is limited by the lack of naturally occurring protease sites in the C-terminal tail of SUMO proteins ...
Ahmad, Alla S +8 more
core +2 more sources
OsteoporosAtlas: a human osteoporosis-related gene database [PDF]
Background Osteoporosis is a common, complex disease of bone with a strong heritable component, characterized by low bone mineral density, microarchitectural deterioration of bone tissue and an increased risk of fracture.
Xun Wang +13 more
doaj +2 more sources
Whole-proteome tree of life suggests a deep burst of organism diversity. [PDF]
An organism tree of life (organism ToL) is a conceptual and metaphorical tree to capture a simplified narrative of the evolutionary course and kinship among the extant organisms.
Choi, JaeJin, Kim, Sung-Hou
core
Proteomics of industrial fungi: trends and insights for biotechnology [PDF]
Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and organic acids.
Oliveira, J.M., Graaff, L.H., de
core +1 more source
Neutrophils and macrophages are both involved in the initiation of inflammation, but whether and how they may participate in inflammation resolution is unclear.
Wenting Yang +10 more
doaj +1 more source
The proteostasis network and its decline in ageing
Ageing is a major risk factor for the development of many diseases, prominently including neurodegenerative disorders such as Alzheimer disease and Parkinson disease.
Hartl, F., Hipp, M., Kasturi, P.
core +1 more source
solveME: fast and reliable solution of nonlinear ME models. [PDF]
BackgroundGenome-scale models of metabolism and macromolecular expression (ME) significantly expand the scope and predictive capabilities of constraint-based modeling.
Ebrahim, Ali +5 more
core +4 more sources
As anucleate cell particles, platelets do not lend themselves to analysis by traditional cell and molecular biology techniques. Moreover, while valuable information may be gleaned from studies of messenger RNA in platelets, the rapid events in platelets are not governed by or dependent on alterations in gene expression.
P B, Maguire, D J, Fitzgerald
openaire +2 more sources

