Results 21 to 30 of about 12,949 (236)

Identification of Arginine Phosphorylation in Mycolicibacterium smegmatis

open access: yesMicrobiology Spectrum, 2022
Tuberculosis is a leading cause of worldwide infectious mortality. The prevalence of multidrug-resistant Mycobacterium tuberculosis infections drives an urgent need to exploit new drug targets.
Emmanuel C. Ogbonna   +2 more
doaj   +1 more source

Phosphorylation-Mediated Molecular Pathway Changes in Human Pituitary Neuroendocrine Tumors Identified by Quantitative Phosphoproteomics

open access: yesCells, 2021
To investigate the biological role of protein phosphorylation in human nonfunctional pituitary neuroendocrine tumors (NF-PitNETs), proteins extracted from NF-PitNET and control tissues were analyzed with tandem mass tag (TMT)-based quantitative ...
Jiajia Li   +4 more
doaj   +1 more source

Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors [PDF]

open access: yes, 2013
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Bart Vanhaesebroeck   +15 more
core   +1 more source

Table containing all phosphoproteomics data. [PDF]

open access: yes, 2022
Phosphoproteomics dataset containing all phosphoproteins detected (Quant tab), mass spectrometry data for all phosphopeptides detected (pep_quant tab), and phosphoproteins with differential phosphorylation patterns (phosphorylation change of 1.5-fold ...
Matthew Pinch (10977270)   +4 more
core   +1 more source

Computational Analysis of Phosphoproteomics: Progresses and Perspectives [PDF]

open access: yes, 2020
: Phosphorylation is one of the most essential post-translational modifications (PTMs) of proteins, regulates a variety of cellular signaling pathways, and at least partially determines the biological diversity.
Qian Ma   +5 more
core   +2 more sources

Impact of Phosphoproteomics in the Era of Precision Medicine for Prostate Cancer

open access: yesFrontiers in Oncology, 2018
Prostate cancer is the most common malignancy in men in the United States. While androgen deprivation therapy results in tumor responses initially, there is relapse and progression to metastatic castration-resistant prostate cancer.
Johnny R. Ramroop   +5 more
doaj   +1 more source

Temporal Quantitative Phosphoproteomics Profiling of Interleukin-33 Signaling Network Reveals Unique Modulators of Monocyte Activation

open access: yesCells, 2022
Interleukin-33 (IL-33), a member of the IL-1 superfamily cytokines, is an endogenous danger signal and a nuclear-associated cytokine. It is one of the essential mediators of both innate and adaptive immune responses.
Devasahayam Arokia Balaya Rex   +7 more
doaj   +1 more source

State‐of‐the‐art in phosphoproteomics [PDF]

open access: yesPROTEOMICS, 2005
Abstract Presently, phosphorylation of proteins is the most studied and best understood PTM. However, the analysis of phosphoproteins and phosphopeptides is still one of the most challenging tasks in contemporary proteome research.
Joerg, Reinders, Albert, Sickmann
openaire   +2 more sources

Phosphoproteomics in cancer

open access: yesMolecular Oncology, 2010
AbstractReversible protein phosphorylation serves as a basis for regulating a number of cellular processes. Aberrant activation of kinase signaling pathways is commonly associated with several cancers. Recent developments in phosphoprotein/phosphopeptide enrichment strategies and quantitative mass spectrometry have resulted in robust pipelines for high‐
H C, Harsha, Akhilesh, Pandey
openaire   +3 more sources

Quantitative phosphoproteomics to characterize signaling networks [PDF]

open access: yes, 2012
Reversible protein phosphorylation is involved in the regulation of most, if not all, major cellular processes via dynamic signal transduction pathways. During the last decade quantitative phosphoproteomics have evolved from a highly specialized area to ...
Blagoev, Blagoy; id_orcid   +3 more
core   +1 more source

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