Results 11 to 20 of about 14,675 (189)
Applications and prospects of phosphoproteomics in renal disease research [PDF]
PeerJIntroduction Phosphoproteomics, an advanced branch of molecular biology, utilizes specific techniques such as mass spectrometry, affinity chromatography, and bioinformatics analysis to explore protein phosphorylation, shedding light on the cellular ...
XueJia Zheng +8 more
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Phosphoproteomics: Methods and Challenges
, 2023 Protein phosphorylation is a widespread post-translational modification that regulates many biological processes. This covalent modification alters the biochemical properties of proteins and can act as an activity switch or as a docking site for protein-protein interactions.
Kang, Taewook +3 more
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Plant phosphoproteomics: An update
PROTEOMICS, 2009 Abstract Phosphoproteomics involves identification of phosphoproteins, precise mapping, and quantification of phosphorylation sites, and eventually, revealing their biological function. In plants, several systematic phosphoproteomic analyses have recently been performed to optimize in vitro
Kersten, B. +6 more
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A Decade of Pollen Phosphoproteomics [PDF]
International Journal of Molecular Sciences, 2021 Angiosperm mature pollen represents a quiescent stage with a desiccated cytoplasm surrounded by a tough cell wall, which is resistant to the suboptimal environmental conditions and carries the genetic information in an intact stage to the female gametophyte.
Božena Klodová, Jan Fíla
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, 2022 Supplementary Data from Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic ...
Chi-Yuan Yao (14312526) +13 more
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Proteomic investigation of the class IA phosphoinositide 3-kinase signalling pathway [PDF]
, 2012 PhDClass IA phosphoinositide 3-kinases (PI3Ks) are a family of enzymes with key roles in the regulation of signalling pathways, many of which are mediated through Akt.
Beltran, Luisa
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Phosphoproteomics for the Masses [PDF]
ACS Chemical Biology, 2010 Protein phosphorylation serves as a primary mechanism of signal transduction in the cells of biological organisms. Technical advancements over the last several years in mass spectrometry now allow for the large-scale identification and quantitation of in vivo phosphorylation at unprecedented levels.
Paul A, Grimsrud +4 more
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Optimized Suspension Trapping Method for Phosphoproteomics Sample Preparation [PDF]
, 2023 A successful mass spectrometry-based phosphoproteomics analysis relies on effective sample preparation strategies. Suspension trapping (S-Trap) is a novel, rapid, and universal method of sample preparation that is increasingly applied in bottom-up ...
Stecker, Kelly E. +8 more
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Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data.
PLoS Computational Biology, 2015 Cell signaling underlies transcription/epigenetic control of a vast majority of cell-fate decisions. A key goal in cell signaling studies is to identify the set of kinases that underlie key signaling events.
Pengyi Yang +5 more
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Frontiers in Physiology, 2023 Human airway smooth muscle (HASM) is the primary target of ßAR agonists used to control airway hypercontractility in asthma and chronic obstructive pulmonary disease (COPD).
Isabella Cattani-Cavalieri +5 more
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