Results 31 to 40 of about 12,949 (236)
Frontiers in Plant Science, 2017 Mass spectrometry (MS)-based large scale phosphoproteomics has facilitated the investigation of plant phosphorylation dynamics on a system-wide scale. However, generating large scale data sets for membrane phosphoproteins usually requires fractionation ...
Xu Na Wu +5 more
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Protein Phosphorylation Changes During Systemic Acquired Resistance in Arabidopsis thaliana
Frontiers in Plant Science, 2021 Systemic acquired resistance (SAR) in plants is a defense response that provides resistance against a wide range of pathogens at the whole-plant level following primary infection.
Qingfeng Zhou +7 more
doaj +1 more source
Bioscience Reports, 2005 Protein phosphorylation is directly or indirectly involved in all important cellular events. The understanding of its regulatory role requires the discovery of the proteins involved in these processes and how, where and when protein phosphorylation takes place.
Roberto, Raggiaschi +2 more
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Phosphoproteomic Profiling of the Myocyte [PDF]
Circulation: Cardiovascular Genetics, 2011 Protein phosphorylation underpins major cellular processes including energy metabolism, signal transduction, excitation-contraction coupling, apoptosis, and cell survival mechanisms and is thus critical to the myocyte. Targeted approaches, whereby a handful of phosphoproteins are investigated, can suffer from a relatively narrow view of cellular ...
Alistair V G, Edwards +2 more
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Phosphoproteomics taken to heart [PDF]
Cell Cycle, 2013 The last decade has witnessed a tremendous advance in mass spectrometric instrumentation, sample preparation, and computational proteomics developments that now make it possible to analyze proteins1 or post-translational modifications (PTMs) of proteins2 on a global scale and compare their relative abundance between different cell states.
Lundby, A., Olsen, J.V.
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Frontiers in Pharmacology, 2021 Platelet hyperactivity is a risk factor for cardiovascular disease and thrombosis. Recent studies reported that the tomato extract Fruitflow inhibited platelet function, but the molecular mechanism is still unclear.
Shenghao Zhang +6 more
doaj +1 more source
Evaluation of DDA Library-Free Strategies for Phosphoproteomics and Ubiquitinomics Data-Independent Acquisition Data [PDF]
Phosphoproteomics and ubiquitinomics data-independent acquisition (DIA) mass spectrometry (MS) data is typically analyzed by using a data-dependent acquisition (DDA) spectral library.
Xiang-Yu Chen (2226904) +10 more
core +13 more sources
eLife, 2016 Neurotransmitter release is mediated by the fast, calcium-triggered fusion of synaptic vesicles with the presynaptic plasma membrane, followed by endocytosis and recycling of the membrane of synaptic vesicles.
Mahdokht Kohansal-Nodehi +4 more
doaj +1 more source
Frontiers in Physiology, 2018 Sea cucumbers exposed to stressful circumstances eviscerate most internal organs, and then regenerate them rapidly under favorable environments. Reversible protein phosphorylation and acetylation are major modifications regulating protein function ...
Lina Sun +15 more
doaj +1 more source
Interrogating the hidden phosphoproteome [PDF]
PROTEOMICS, 2017 Postgenomic studies continue to highlight the potential clinical importance of protein phosphorylation signaling pathways in drug discovery. Unfortunately, the dynamic range and variable stoichiometry of protein phosphorylation continues to stymie efforts to achieve comprehensive characterization of the human phosphoproteome.
Un-Beom, Kang +2 more
openaire +2 more sources