Results 51 to 60 of about 27,576 (286)

Phosphorylation is required for the pathogen defense function of the Arabidopsis PEN3 ABC transporter. [PDF]

, 2017
The Arabidopsis PEN3 ABC transporter accumulates at sites of pathogen detection, where it is involved in defense against a number of pathogens. Perception of PAMPs by pattern recognition receptors initiates recruitment of PEN3 and also leads to PEN3 ...
Somerville, Shauna, Underwood, William
core   +1 more source

Interrogating the hidden phosphoproteome [PDF]

PROTEOMICS, 2017
Postgenomic studies continue to highlight the potential clinical importance of protein phosphorylation signaling pathways in drug discovery. Unfortunately, the dynamic range and variable stoichiometry of protein phosphorylation continues to stymie efforts to achieve comprehensive characterization of the human phosphoproteome.
Un-Beom, Kang, William M, Alexander, Jarrod A, Marto   +2 more
openaire   +2 more sources

HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread [PDF]

, 2016
open access articleHIV-1 spreads between CD4 T cells most efficiently through virus-induced cell-cell contacts. To test whether this process potentiates viral spread by activating signaling pathways, we developed an approach to analyze the ...
Jolly, Clare, Len, Alice C.L., Shivkumar, Maitreyi, Starling, Shimona   +3 more
core   +2 more sources

Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets

Frontiers in Pharmacology, 2021
Platelet hyperactivity is a risk factor for cardiovascular disease and thrombosis. Recent studies reported that the tomato extract Fruitflow inhibited platelet function, but the molecular mechanism is still unclear.
Shenghao Zhang, Huilian Chen, Chuanbao Li, Beidong Chen, Huan Gong, Yanyang Zhao, Ruomei Qi   +6 more
doaj   +1 more source

Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosis

eLife, 2016
Neurotransmitter release is mediated by the fast, calcium-triggered fusion of synaptic vesicles with the presynaptic plasma membrane, followed by endocytosis and recycling of the membrane of synaptic vesicles.
Mahdokht Kohansal-Nodehi, John JE Chua, Henning Urlaub, Reinhard Jahn, Dominika Czernik   +4 more
doaj   +1 more source

A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane [PDF]

, 2008
Proteomic and phosphoproteomic analyses of rice shoot and root tonoplast-enriched and plasma membrane-enriched membrane fractions were carried out to look at tissue-specific expression, and to identify putative regulatory sites of membrane transport ...
Ahn, Alexandersson, Armengaud, Banuelos, Benschop, Brugiere, Carter, Chrispeels, Ducos, Dunkley, Endler, Gaxiola, Gierth, Jacquinod, Komatsu, Larsson, Loque, Lüttge, Ma, Maathuis, Maathuis, Marmagne, Morsomme, Niittyla, Nühse, Nühse, Paszkowski, Peltier, Pighin, Rentsch, Sancenon, Tanaka, Tornroth-Horsefield, Toyofuku, Vitart, Whiteman, Wintz, Wu, Yazaki   +38 more
core   +1 more source

Proteomics and Phosphoproteomics of Circulating Extracellular Vesicles Provide New Insights into Diabetes Pathobiology

International Journal of Molecular Sciences, 2022
The purpose of this study was to define the proteomic and phosphoproteomic landscape of circulating extracellular vesicles (EVs) in people with normal glucose tolerance (NGT), prediabetes (PDM), and diabetes (T2DM).
Y. O. Nunez Lopez, A. Iliuk, A. M. Petrilli, Carley E. Glass, A. Casu, R. Pratley   +5 more
semanticscholar   +1 more source

Comparative Phospho- and Acetyl Proteomics Analysis of Posttranslational Modifications Regulating Intestine Regeneration in Sea Cucumbers

Frontiers in Physiology, 2018
Sea cucumbers exposed to stressful circumstances eviscerate most internal organs, and then regenerate them rapidly under favorable environments. Reversible protein phosphorylation and acetylation are major modifications regulating protein function ...
Lina Sun, Lina Sun, Chenggang Lin, Chenggang Lin, Xiaoni Li, Xiaoni Li, Lili Xing, Lili Xing, Da Huo, Da Huo, Jingchun Sun, Jingchun Sun, Libin Zhang, Libin Zhang, Hongsheng Yang, Hongsheng Yang   +15 more
doaj   +1 more source

Proteomics of industrial fungi: trends and insights for biotechnology [PDF]

, 2010
Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and organic acids.
Oliveira, J.M., Graaff, L.H., de
core   +1 more source

GPER-induced signaling is essential for the survival of breast cancer stem cells. [PDF]

, 2020
G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells.
Chan, Yu-Tzu, Chang, Wen-Wei, Chang, Wen-Ying, Chen, Yu-Ju, Lai, Alan C-Y, Lin, Ruey-Jen, Lin, Yu-Ju, Wang, Ya-Hui, Wang, Yi-Ting, Wu, Hsin-Yi, Wu, Jen-Chine, Yu, Alice L, Yu, Jyh-Cherng   +12 more
core   +2 more sources