Results 131 to 140 of about 1,164,549 (348)

The DLG processor: A data management executive for the engineering design integration (EDIN) system. Volume 1: Engineering description and utilization manual [PDF]

open access: yes
The DLG processor is a Univac 1100 series computer program designed to read, modify, manipulate, and replace symbolic images. DLG is controlled by a set of user supplied directives and operates from a data base of stratified information which can be ...
Colquitt, W. N., Glatt, C. R.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Online data storage service strategy for the CERN computer Centre [PDF]

open access: diamond, 2011
G Cancio   +3 more
openalex   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Identifying Non-Volatile Data Storage Areas: Unique Notebook Identification Information as Digital Evidence

open access: yesJournal of Digital Forensics, Security and Law, 2007
The research reported in this paper introduces new techniques to aid in the identification of recovered notebook computers so they may be returned to the rightful owner.
Nikica Budimir, Jill Slay
doaj  

Computer knowledge in the field of personal archiving: an exploratory study based on grounded theory

open access: yesInformation Research: An International Electronic Journal
Introduction. Personal archiving has transformed from traditional general knowledge to literacy-oriented ability, which requires professional knowledge and skills in the digital age.
Tiyang Huang, Qingyun Pu, Li Zhang
doaj   +1 more source

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