A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Back‐dropout transfer learning for action recognition
IET Computer Vision, 2018 Transfer learning aims at adapting a model learned from source dataset to target dataset. It is a beneficial approach especially when annotating on the target dataset is expensive or infeasible.
Huamin Ren +7 more
doaj +1 more source
COMPUTER-AIDED DESIGN OF THE VIVALDI ANTENNA FOR ULTRA-WIDEBAND ELECTROMAGNETIC PULSE RADIATION
, 2021 A.I. Mel’nichuk +2 more
openalex +1 more source
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems society information [PDF]
, 2021 Yao-Wen Chang +38 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Fine-Tuned IndoBERT for Aspect-Based Sentiment Analysis of Indonesian Five-Star Hotel Reviews
Jurnal SisfokomOnline reviews significantly shape public perception and play a crucial role in customer decision-making within the hospitality sector. This research aims to conduct aspect-based sentiment analysis on Indonesian five-star hotel reviews using a fine-tuned
Sinta Apriliani +2 more
doaj +1 more source
Computer-assisted design of organic synthesis [PDF]
The computer programs to design synthetic pathways of organic compounds have been utilized throughout the world since the first system was reported by Corey in 1969, and the LHASA was reported in1972 to become the predominant system.
Kaminaka, H.
core +1 more source
Computer program simplifies design of rotating components of turbomachinery [PDF]
, 1967 Digital computer program performs stress analysis and burst speed calculations on rotating axisymmetric turbomachinery components. The computer printout contains the displacement of each nodal point, the stress at the center of each element, the average ...
Lefevre, J. C.
core +1 more source
Computer-aided molecular design
Computer-Aided Design, 1985 Abstract Computer-aided molecular design has come of age. In the pharmaceutical and fine chemical industries computer graphics techniques allied to theoretical calculations are proving successful in suggesting to synthetic chemists molecules which will merit synthesis in terms of desired specific properties.
openaire +2 more sources