Results 91 to 100 of about 606,472 (339)
Multi-agent evolutionary systems for the generation of complex virtual worlds
, 2016 Modern films, games and virtual reality applications are dependent on convincing computer graphics. Highly complex models are a requirement for the successful delivery of many scenes and environments.
Connor, Andy M., Kruse, Jan
core +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Computer graphics for metaverse
Virtual Reality & Intelligent Hardware, 2022 Nadia Magnenat Thalmann +4 more
doaj +1 more source
Broadening the interface bandwidth in simulation based training [PDF]
Currently most computer based simulations rely exclusively on computer generated graphics to create the simulation. When training is involved, the method almost exclusively used to display information to the learner is text displayed on the cathode ray ...
Somers, Larry E.
core +1 more source
A Network Compatible Display Protocol [PDF]
, 1979 At present IIASA offers to its scientific community a set of basic, but limited computer graphics capabilities. Recent computer-program development in the graphics area has created greater demand and more awareness of the possibilities of computer ...
Schweeger, B.
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Design and implementation of virtual reality instructional tools for 3D printing processes in digital manufacturing [PDF]
Journal of Intelligent Manufacturing and Special EquipmentPurpose – In order to allow easy replication of this study, industry standard software that is easily attainable was used. Most of the programs used are free to download, and the ones that are not are available, students can still obtain them through ...
Daniel Cubillos, Magesh Chandramouli
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source