Results 111 to 120 of about 2,707,410 (256)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Efficient workflow scheduling using an improved multi-objective memetic algorithm in cloud-edge-end collaborative framework

Scientific Reports
With the rapid advancement of large-scale model technologies, AI agent frameworks built on foundation models have become a central focus of artificial-intelligence research.
Guangzhang Cui, Wei Zhang, Weiwei Xu, Hujun Bao   +3 more
doaj   +1 more source

Retracted: Visualization Display System of Gannan Hakka Paper-Cut Works Based on Computer Graphics Algorithm. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Manipulating Pixels in Computer Graphics by Converting Raster Elements to Vector Shapes as a Function of Hue. [PDF]

J Imaging, 2023
Koren Ivančević T, Stanić Loknar N, Rudolf M, Bratić D.   +3 more
europepmc   +1 more source

Decoupled Sampling for Real-Time Graphics Pipelines [PDF]

, 2010
We propose decoupled sampling, an approach that decouples shading from visibility sampling in order to enable motion blur and depth-of-field at reduced cost.
Ragan-Kelley, Jonathan, Doggett, Michael, Lehtinen, Jaakko, Durand, Fredo, Chen, Jiawen   +4 more
core  

Computer graphics: from desktop to mobile and web [PDF]

, 2011
“© © 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Esparza Peidro, Javier, Jordi Linares-Pellicer, Empar Carrasquer-Moya, Pau Micó, Linares-Pellicer, Jordi, Micó Tormos, Pau, Javier Esparza-Peidro, Carrasquer Moya, Maria Amparo   +7 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Machine learning and AI in graphics development [PDF]

E3S Web of Conferences
The fusion of software computer graphics and development technologies has revolutionized the digital landscape, opening new frontiers in visual storytelling, interactive experiences, and digital innovation.
Umarov Husan, Mirzaraimova Vasila, Yakubova Muyassar, Tashpulatov Ravshanbek   +3 more
doaj   +1 more source

Quantitative Measurement of Morphological Characteristics of PTFE Composite Transfer Films Based on Computer Graphics. [PDF]

Materials (Basel), 2023
Qi Y, Sun B, Wang H, Zhang Y, Gao G, Zhang P, Zheng X.   +6 more
europepmc   +1 more source