Results 91 to 100 of about 105,839 (315)

Hardware accelerated computer graphics algorithms

open access: yes, 2008
The advent of shaders in the latest generations of graphics hardware, which has made consumer level graphics hardware partially programmable, makes now an ideal time to investigate new graphical techniques and algorithms as well as attempting to improve ...
Rhodes, Daniel Thomas, Rhodes, DT
core  

Computer graphics: from desktop to mobile and web [PDF]

open access: yes, 2011
“© © 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new ...
Esparza Peidro, Javier   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A Novel Camera Calibration Algorithm as Part of an HCI System: Experimental Procedure and Results [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2006
Camera calibration is an initial step employed in many computer vision applications for the estimation of camera parameters. Along with images of an arbitrary scene, these parameters allow for inference of the scene's metric information.
Sauer Kristal   +3 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Evaluation of tribo-vibration characteristics of the finishing turning process of heat-resistant structural steel 20MnMoNi5-5 [PDF]

open access: yesE3S Web of Conferences
This article is devoted to determining the rational range of cutting speeds during longitudinal finish turning of heat-resistant steel 20MnMoNi5-5 based on a set of tribological and vibration parameters of the cutting process.
Gvindjiliya Valery   +3 more
doaj   +1 more source

Decoupled Sampling for Real-Time Graphics Pipelines [PDF]

open access: yes, 2010
We propose decoupled sampling, an approach that decouples shading from visibility sampling in order to enable motion blur and depth-of-field at reduced cost.
Ragan-Kelley, Jonathan   +4 more
core  

Design and implementation of virtual reality instructional tools for 3D printing processes in digital manufacturing [PDF]

open access: yesJournal of Intelligent Manufacturing and Special Equipment
Purpose – In order to allow easy replication of this study, industry standard software that is easily attainable was used. Most of the programs used are free to download, and the ones that are not are available, students can still obtain them through ...
Daniel Cubillos, Magesh Chandramouli
doaj   +1 more source

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