Results 131 to 140 of about 105,839 (315)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
3D modeling and reconstruction of plants and trees: A cross-cutting review across computer graphics, vision, and plant phenotyping. [PDF]
Breed Sci, 2022 Okura F.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Graphics and Visualization within Cross-Stitch [PDF]
, 1999 The leisure industry, in fields such as the games market, is immersed in computer graphics. However, non-traditional visualization techniques are slow to appear within many leisure pursuits especially cross-stitch.
Atkinson, Karen R., Roberts, Jonathan C.
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Mobile Presence - a Computer Graphics Utopia?
, 2022 S.135-138In this paper we set out a future scenario of mobile presence. We will define our understanding of the term mobile presence. We will derive the requirements imposed by mobile presence with respect to computer graphics and computer graphics ...
Danch, Daniel, Stork, André
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Non-photorealistic computer graphics: modeling, rendering, and animation
, 2002 Even as developments in photorealistic computer graphics continue to affect our work and leisure activities, practitioners and researchers are devoting more and more attention to non-photorealistic (NPR) techniques for generating images that appear to ...
Schlechtweg, Stefan. +2 more
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Computer Graphics Programming: GKS - the graphics standard
, 1984 Covers computer graphics programming on the basis of the Graphical Kernel System. It gives an overview over the GKS concepts, the history of the GKS design and the various system interfaces. A detailed description of the application of GKS functions both
K. Kansy +5 more
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