Results 121 to 130 of about 2,707,410 (256)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A reinterpretation of the gap fraction of tree crowns from the perspectives of computer graphics and porous media theory. [PDF]
Front Plant Sci, 2023 Zhu Y +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Visualization of the complex double-outlet right ventricle anatomy using real-time three-dimensional computer graphics. [PDF]
JTCVS Tech, 2023 Omori A, Inuzuka R, Hirata Y.
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Selected Readings in Computer Graphics 2008
, 2022 The Fraunhofer Institute for Computer Graphics Research IGD with offices in Darmstadt as well as in Rostock and Graz, the partner institutes at the respective universities, the Interactive Graphics System Group of Technische Universität Darmstadt, the ...
core +1 more source
A new group-based online job interview training program using computer graphics robots for individuals with autism spectrum disorders. [PDF]
Front Psychiatry, 2023 Yoshikawa Y +7 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Shortwave Radiation Calculation for Forest Plots Using Airborne LiDAR Data and Computer Graphics. [PDF]
Plant Phenomics, 2022 Xue X +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source