Results 71 to 80 of about 596,236 (288)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
On the Provision of a Comprehensive Computer Graphics Education in the Context of Computer Games [PDF]
, 2009 Position paper for the ACM SIGGRAPH/Eurographics Computer Graphics Education Workshop ...
Anderson, Eike F., Peters, CE
core
Smoke and Shadows: Rendering and Light Interaction of Smoke in Real-Time Rendered Virtual Environments [PDF]
, 2013 Realism in computer graphics depends upon digitally representing what we see in the world with careful attention to detail, which usually requires a high degree of complexity in modelling the scene.
Anderson, Eike F., Bass, C. J.
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Interactive graphical computer-aided design system [PDF]
, 1975 System is used for design, layout, and modification of large-scale-integrated (LSI) metal-oxide semiconductor (MOS) arrays. System is structured around small computer which provides real-time support for graphics storage display unit with keyboard, slave
Edge, T. M.
core +1 more source
Journal of Imaging, 2018 Drones are becoming increasingly popular for remote sensing of landscapes in archeology, cultural heritage, forestry, and other disciplines. They are more efficient than airplanes for capturing small areas, of up to several hundred square meters.
Indrajit Kurmi +2 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Overview of crowd simulation in computer graphics [PDF]
, 2008 High-powered technology use computer graphics in education, entertainment, games, simulation, and virtual heritage applications has led it to become an important area of research. In simulation, according to Tecchia et al.
Daman, Daut, Mohamed Azahar, Mohamed Adi
core
Multi-agent evolutionary systems for the generation of complex virtual worlds
, 2016 Modern films, games and virtual reality applications are dependent on convincing computer graphics. Highly complex models are a requirement for the successful delivery of many scenes and environments.
Connor, Andy M., Kruse, Jan
core +2 more sources
Generation and Validation of Osseous Fracture Patterns by Forensic Analysis
IEEE Access, 2020 This article presents a method for the generation of bone fracture patterns and their automatic validation through the use of forensic analysis. A tool has been designed that allows the generation of a fracture pattern interactively and guided by the ...
J. J. Jimenez-Delgado +3 more
doaj +1 more source