Results 81 to 90 of about 596,236 (288)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

VR and HCI Labs at the Czech Technical University in Prague

open access: yesJournal on Interactive Systems, 2011
Nenhum resumo ...
Roman Berka, Jiri Bittner, Pavel Slavik
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The use of graphics in the design of the human-telerobot interface [PDF]

open access: yes
The Man-Systems Telerobotics Laboratory (MSTL) of NASA's Johnson Space Center employs computer graphics tools in their design and evaluation of the Flight Telerobotic Servicer (FTS) human/telerobot interface on the Shuttle and on the Space Station.
Smith, Randy L., Stuart, Mark A.
core   +1 more source

3D computer graphics [PDF]

open access: yes, 2016
3D computer graphics (in contrast to 2D computer graphics) are graphics that utilize a three-dimensional representation of geometric data that is stored in the computer for the purposes of performing calculations and rendering 2D ...
Sheremereyevych, D.
core  

A Novel Camera Calibration Algorithm as Part of an HCI System: Experimental Procedure and Results [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2006
Camera calibration is an initial step employed in many computer vision applications for the estimation of camera parameters. Along with images of an arbitrary scene, these parameters allow for inference of the scene's metric information.
Sauer Kristal   +3 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Computer graphics application in the engineering design integration system [PDF]

open access: yes
The computer graphics aspect of the Engineering Design Integration (EDIN) system and its application to design problems were discussed. Three basic types of computer graphics may be used with the EDIN system for the evaluation of aerospace vehicles ...
Abel, R. W.   +5 more
core   +1 more source

Evaluation of tribo-vibration characteristics of the finishing turning process of heat-resistant structural steel 20MnMoNi5-5 [PDF]

open access: yesE3S Web of Conferences
This article is devoted to determining the rational range of cutting speeds during longitudinal finish turning of heat-resistant steel 20MnMoNi5-5 based on a set of tribological and vibration parameters of the cutting process.
Gvindjiliya Valery   +3 more
doaj   +1 more source

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