Results 81 to 90 of about 3,233,093 (388)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Generation and Validation of Osseous Fracture Patterns by Forensic Analysis
This article presents a method for the generation of bone fracture patterns and their automatic validation through the use of forensic analysis. A tool has been designed that allows the generation of a fracture pattern interactively and guided by the ...
J. J. Jimenez-Delgado +3 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Drones are becoming increasingly popular for remote sensing of landscapes in archeology, cultural heritage, forestry, and other disciplines. They are more efficient than airplanes for capturing small areas, of up to several hundred square meters.
Indrajit Kurmi +2 more
doaj +1 more source
Simulation and Computer Graphics
In these four pages, this paper can be neither a complete introduction nor a complete survey of the role of computer graphics in simulation. However, these examples drawn from the experience of the Naval Post graduate School computer laboratory will illustrate a wide class of applications which may suggest uses in other fields.
openaire +3 more sources
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
VR and HCI Labs at the Czech Technical University in Prague
Nenhum resumo ...
Roman Berka, Jiri Bittner, Pavel Slavik
doaj +1 more source
Semantic 3D Reconstruction with Learning MVS and 2D Segmentation of Aerial Images
Semantic modeling is a challenging task that has received widespread attention in recent years. With the help of mini Unmanned Aerial Vehicles (UAVs), multi-view high-resolution aerial images of large-scale scenes can be conveniently collected.
Zizhuang Wei +4 more
doaj +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
The use of graphics in the design of the human-telerobot interface [PDF]
The Man-Systems Telerobotics Laboratory (MSTL) of NASA's Johnson Space Center employs computer graphics tools in their design and evaluation of the Flight Telerobotic Servicer (FTS) human/telerobot interface on the Shuttle and on the Space Station.
Smith, Randy L., Stuart, Mark A.
core +1 more source

