Results 91 to 100 of about 5,120,531 (253)
Automated testing of computer graphics systems
, 2022 S.L1-L11 : Abb.,Lit.Graphics Systems have become increasingly complex over the last years. Computer Graphics standards provide the means to implement portable graphics applications.
Goebel, M., Jorge, J., Ziegler, R.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Computer graphics techniques for modeling page turning [PDF]
, 2007 Turning the page is a mechanical part of the cognitive act of reading that we do literally unthinkingly. Interest in realistic book models for digital libraries and other online documents is growing.
Witten, Ian H., Liesaputra, Veronica
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Selected Readings in Computer Graphics 2009. CD-ROM
, 2022 The Fraunhofer Institute for Computer Graphics Research IGD with offices in Darmstadt as well as in Rostock, Singapore, and Graz, the partner institutes at the respective universities, the Interactive Graphics Systems Group of Technische Universität ...
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
GENERIC COORDINATE SYSTEMS IN THE COMPUTER GEOMETRY COURSE
Современные информационные технологии и IT-образование, 2018 The article presents an approach to describe generic coordinate systems as a part of the course “Computer Geometry and Geometric Modeling”, which is taught to third-year students majoring in mathematics at the Lobachevsky State University of Nizhni ...
Evgeny M. Makarov
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Non-photorealistic computer graphics: modeling, rendering, and animation
, 2002 Even as developments in photorealistic computer graphics continue to affect our work and leisure activities, practitioners and researchers are devoting more and more attention to non-photorealistic (NPR) techniques for generating images that appear to ...
Schlechtweg, Stefan. +2 more
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