Results 41 to 50 of about 55,185 (265)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

ZC Simulator Implementation in TECIS Computer Interlocking Testing for Zhangjiang Test Line

机车电传动, 2017
A ZC simulator using the agile development model for functional testing of computer interlocking system was introduced from the functional requirements, design architecture, implementation method and application situation.
LI Pengdong, CHEN Xin, REN Ying, YANG Xiaorong   +3 more
doaj  

An interlocking system determining the configuration of rail traffic control elements to ensure safety

AIMS Mathematics
Railway interlocking systems are essential safety components in rail transportation, designed to prevent train collisions. They regulate the transitions between sections of a railway station using rail traffic control elements. An interlocking system can
Antonio Hernando, Gabriel Aguilera-Venegas , José Luis Galán-García, Sheida Nazary   +3 more
doaj   +1 more source

Bio-Modules: Mycelium-Based Composites Forming a Modular Interlocking System through a Computational Design towards Sustainable Architecture

Designs, 2023
In a resource-constrained world, raising awareness about the development of eco-friendly alternative materials is critical for ensuring a more sustainable future. Mycelium-based composites (MBC) and their diverse applications are gaining popularity as regenerative, biodegradable, and lightweight alternatives.
Omar Abdelhady, Evgenia Spyridonos, Hanaa Dahy   +2 more
openaire   +4 more sources

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Modelling of Failure Effect to Integrity of System

Advances in Electrical and Electronic Engineering, 2004
The interlocking systems are typically resisting against hazardous faults. Failure effect on the system can be determined directly by monitoring the original system installation, by simulation of the system operation using its model, or by computing or ...
Karol Rastocny
doaj  

Research on the Solution of Train-trackside CooperativeShortening Movement Authority

Kongzhi Yu Xinxi Jishu, 2020
In railway operations, when an opened route needs to be closed occasionally, the approach locking function of interlocking is needed to avoid the trip risk of a train.
LI Qihe
doaj  

Evaluation of pressure-stiffness coupling in brush seals [PDF]

, 2010
Brush seals are comprised of fine diameter fibers densely packed between retaining and backing plates. To achieve seal compliance bristles are arranged to contact rotor with some lay angle.
Aksit, Mahmut Faruk, Aksoy, Serdar, Akşit, Mahmut Faruk   +2 more
core   +1 more source

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Quantitative Safety Analysis of Train Control System Considering Common Cause Failure

Kongzhi Yu Xinxi Jishu
The train control system, a safety-related component pivotal for ensuring the operational safety of trains, is prone to causing common cause failures (CCF) due to its multi-channel redundancy design.
LUO Jiguang
doaj   +3 more sources