Results 111 to 120 of about 1,880,786 (300)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Levels-based Approach for Defining Software Measurement Architectures
CLEI Electronic Journal, 2014 During the execution of software projects, it is necessary to collect, store and analyze data to support project and organizational decisions. Software measurement is a fundamental practice for project management and process improvement. It is present in
Ciro Xavier Maretto +1 more
doaj +1 more source
Evaluation of aerothermal modeling computer programs [PDF]
Various computer programs based upon the SIMPLE or SIMPLER algorithm were studied and compared for numerical accuracy, efficiency, and grid dependency.
Hsieh, K. C., Yu, S. T.
core +1 more source
Systematic and multifactor risk models revisited [PDF]
, 2013 Systematic and multifactor risk models are revisited via methods which were already successfully developed in signal processing and in automatic control.
Fliess, Michel, Join, Cédric
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
NASTRAN applications to aircraft propulsion systems [PDF]
, 1975 The use of NASTRAN in propulsion system structural integration analysis is described. Computer support programs for modeling, substructuring, and plotting analysis results are discussed.
Beste, D. L., White, J. L.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Three-Dimensional Photography and Computer Modeling as a Reconstructive Surgical Training Tool. [PDF]
Aesthet Surg J Open Forum, 2023 Singh P +5 more
europepmc +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source