Results 111 to 120 of about 2,661,670 (316)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

A digital communication network for computers giving rapid response at remote terminals [PDF]

open access: bronze, 1967
D. W. Davies   +3 more
openalex   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Overcoming Illegal Cross-border Transfer of Personal Data

open access: yesJournal of Digital Technologies and Law
Objective: to form of a comprehensive interdisciplinary legal and technological risk management model in the field of illegal cross-border transfer of personal data by eliminating legislative gaps and creating a system for automated control of outgoing ...
D. V. Bakhteev   +2 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Advance system and model to predict malicious files prorogation inside computer network

open access: yesIET Networks, 2019
A new model for malicious file propagation and transmission in a computer network is formulated. This model introduced a cure rate ξ (E ‐cure rate) which is calculated after the regular running of anti‐virus in the systems of the computer network.
Ashraf Ahmad   +2 more
doaj   +1 more source

The network computer.

open access: yesJournal of Information Processing and Management, 1997
パーソナル・コンピュータは,ますます高機能化するとともにハードウエアやネットワーク,またオペレーティング・システムやアプリケーションソフトウエアなどの整備において利用者側が負担するコストも大幅に増加する傾向にある。このような背景のもとに,アップル社,IBM社,オラクル社,ネットスケープ社とサン・マイクロシステムズ社の5社は1996年5月に,「ネットワーク・コンピュータ リファレンス プロファイル」と呼ぶ簡素化した新しいコンピュータの規格策定に合意した。ネットワーク・コンピュータは,ネットワーク接続を前提に装備を極力省いた構成となっている。
openaire   +3 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy