Results 101 to 110 of about 7,199,600 (258)

Queuing system GI/M/1/N with randomly dropping packets mechanism

open access: yesTongxin xuebao, 2006
For the original GI/M/1/N queuing system was not suitable to model the queue management mechanism,a queuing system GI/M/1/N with randomly dropping packets mechanism was discussed by means of thinning of recurrent flows.In addition,the packet loss rate ...
WANG Hao1, LI Xiao-ming1
doaj  

Development of the analytical model and method of optimization of the priority service corporate computer "Elections" network

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
The main objective of this article is to provide recommendations for improving the quality of service indicators in priority service corporate computer networks, including the probability of denial of service attacks, the probability of timely and ...
Zakir Nasib Huseynov
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

A deep learning framework for scientific chart data extraction and reconstruction

open access: yesCommunications Engineering
Scientific figures encapsulate key empirical evidence and are critical to data-driven discovery and scientific integrity assessment. Despite substantial advances in scientific natural language processing for scientific document analysis, automatic ...
Yang Yuan   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Response mechanism for defending computer networks

open access: yes, 2006
With the significant reliance of proactive monitoring of computer networks on security information management systems, a requirement is to provide appropriate and comprehensive countermeasures to perceived threats on the entire network.
Lenaghan, A.P., Onwubiko, C.
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Catholic Women's Network, July / August, 1996

open access: yes, 1996
Digitized version of a newspaper published by the Catholic Women's Network (CWN), a non-profit educational organization for women's spirituality and personal growth.
Catholic Women's Network (Sunnyvale, Calif);
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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