Results 101 to 110 of about 7,199,600 (258)
Queuing system GI/M/1/N with randomly dropping packets mechanism
For the original GI/M/1/N queuing system was not suitable to model the queue management mechanism,a queuing system GI/M/1/N with randomly dropping packets mechanism was discussed by means of thinning of recurrent flows.In addition,the packet loss rate ...
WANG Hao1, LI Xiao-ming1
doaj
The main objective of this article is to provide recommendations for improving the quality of service indicators in priority service corporate computer networks, including the probability of denial of service attacks, the probability of timely and ...
Zakir Nasib Huseynov
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A deep learning framework for scientific chart data extraction and reconstruction
Scientific figures encapsulate key empirical evidence and are critical to data-driven discovery and scientific integrity assessment. Despite substantial advances in scientific natural language processing for scientific document analysis, automatic ...
Yang Yuan +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Response mechanism for defending computer networks
With the significant reliance of proactive monitoring of computer networks on security information management systems, a requirement is to provide appropriate and comprehensive countermeasures to perceived threats on the entire network.
Lenaghan, A.P., Onwubiko, C.
core
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Catholic Women's Network, July / August, 1996
Digitized version of a newspaper published by the Catholic Women's Network (CWN), a non-profit educational organization for women's spirituality and personal growth.
Catholic Women's Network (Sunnyvale, Calif);
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

