Results 111 to 120 of about 638,465 (316)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Large scale network worm detection using automatic signature extraction

open access: yesTongxin xuebao, 2006
Worms had done serious harm to the computer networks due to their propagating speeds.The research was necessary to detect worms quickly and automatically.In large scale networks,flux based anomaly found module was used to screen out anomalous network ...
WANG Ping, FANG Bin-xing, YUN Xiao-chun
doaj  

Initiating and Sustaining Female Networks in Computer Science and IT

open access: yes, 2007
Over the last decade, several networks and communities for women in IT have been initiated. It has been known that specific needs for support exist where members of a minority have difficulties in finding like-minded people in their everyday environment.
Oelinger, Maria, Hinze, Annika
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Limitations of Passively Mapping Logical Network Topologies

open access: yes, 2017
Understanding logical network connectivity is essential in network topology mapping especially in a fast growing network where knowing what is happening on the network is critical for security purposes and where knowing how network resources are being ...
Fidge, Colin   +2 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Mobile network System of Bhadravathi Town using Remote Sending, GIS

open access: yes, 2011
The use of wireless systems is a very attractive option in the design and development of communication networks, especially with the expansion of cellular telephony and wireless computer networks as their industries seek to increase the number of ...
Dr. Basavaraja Simpi
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Elsevier's Journal of Network and Computer Applications

open access: yes
Managing Editor-in-Chief M. Atiquzzaman Journal Metrics Impact Factor: 2.331 5-Year Impact Factor: 2.485 Source Normalized Impact per Paper (SNIP): 2.762 SCImago Journal Rank (SJR): 1.100 The Journal of Network and Computer Applications ...
BONONI, LUCIANO
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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