Results 81 to 90 of about 7,199,600 (258)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Mobile network System of Bhadravathi Town using Remote Sending, GIS [PDF]

open access: yes, 2011
The use of wireless systems is a very attractive option in the design and development of communication networks, especially with the expansion of cellular telephony and wireless computer networks as their industries seek to increase the number of ...
Dr. Basavaraja Simpi
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Overcoming Illegal Cross-border Transfer of Personal Data

open access: yesJournal of Digital Technologies and Law
Objective: to form of a comprehensive interdisciplinary legal and technological risk management model in the field of illegal cross-border transfer of personal data by eliminating legislative gaps and creating a system for automated control of outgoing ...
D. V. Bakhteev   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Improving the Efficiency of Computer Networks Based on the Use of Seamless Wi-Fi Technology—The Use of Artificial Intelligence for Sustainable Agriculture

open access: yesApplied Sciences
Improving the performance of computer networks using seamless Wi-Fi can be achieved by implementing a number of strategies and technologies. Strategies include, first of all, the optimal location of routers and access points, the use of a multi-band ...
Anita Konieczna   +11 more
doaj   +1 more source

A case study on computer and network literacy of upper elementary graders in Taichung

open access: yes, 2011
[[abstract]]The purposes of this study are to explore the computer and network literacy of elementary school students, to compare the background differences among elementary school students, and to examine the relationship between the computer and the ...
Keh-Ming Lu
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Large scale network worm detection using automatic signature extraction

open access: yesTongxin xuebao, 2006
Worms had done serious harm to the computer networks due to their propagating speeds.The research was necessary to detect worms quickly and automatically.In large scale networks,flux based anomaly found module was used to screen out anomalous network ...
WANG Ping, FANG Bin-xing, YUN Xiao-chun
doaj  

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