Results 141 to 150 of about 638,465 (316)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Design of an Associative Processing system for Network Monitoring
, 2000 This paper looks at the design of an embedded processor to be used for network traffic monitoring. This would operate on the stream of data between a network interface and a host computer.
Tripp, Gerald
core
Network emulation focusing on QoS-Oriented satellite communication [PDF]
, 2007 This chapter proposes network emulation basics and a complete case study of QoS-oriented Satellite ...
Dairaine, Laurent +2 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
INVESTIGATION OF CHANGES IN THE LEVEL OF NETWORK SECURITY BASED ON A COGNITIVE APPROACH
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie ŚrodowiskaA study was conducted on the impact of the most significant threats on the level of network security based on the examination of impulse processes on a fuzzy cognitive map.
Olha Saliieva, Yurii Yaremchuk
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Exploration of computer network technology and security management and maintenance
With the rapid development of computer network technology, people’s production and lifestyle have undergone great changes. Due to the universal application and promotion of computer network in all walks of life, coupled with the deepening of smart ...
Liu, Quan; China University of Geosciences /Beijing/ Information Network and Data Center
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source