Results 161 to 170 of about 638,465 (316)

The Computer Science Network.

open access: yesAI Mag., 1982
The CSNET project, sponsored by the National Science Foundation, has as its goal the design and implementation of a computer communications network to provide services to computer science research groups in the United States. Experience with Arpanet has shown that access to a computer network can lead to significantly higher level of interaction ...
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Universal active network architecture and prototype application based on mobile agent technology

open access: yesTongxin xuebao, 2005
A universal active network architecture based on mobile agent technology was proposed, also a prototype application—active search engine founded on this architecture was put forward.
LIAO Xiao-fei   +4 more
doaj  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Evolving discrete-valued anomaly detectors for a network intrusion detection system using negative selection

open access: yes, 2006
Network intrusion detection is the problem of detecting unauthorised use of, or access to, computer systems over a network. One approach is anomaly detection, where deviations from a model of normal network activity are reported.
Powers, Simon T., He, Jun
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Impact of Network Sharing in Multi-core Architectures

open access: yes, 2008
As commodity components continue to dominate the realm of high-end computing, two hardware trends have emerged as major contributors to this - high-speed networking technologies and multi-core architectures.
Narayanaswamy, Ganesh   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Coding method and application for complicated river network based on surveyed river network

open access: yes, 2011
The paper takes National Topographic Database by assuming vector diagram water system with 1:250,000 scale as a data source. A reasonable and efficient coding method for river network is presented, which can solve the coding problem of converged river ...
Jin, Feng, Chen XL(陈雪莲)
core  

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