Results 41 to 50 of about 2,833,464 (263)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Statistical Comparison among Brain Networks with Popular Network Measurement Algorithms [PDF]

arXiv, 2022
In this research, a number of popular network measurement algorithms have been applied to several brain networks (based on applicability of algorithms) for finding out statistical correlation among these popular network measurements which will help scientists to understand these popular network measurement algorithms and their applicability to brain ...
arxiv  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A Study of Basic 3D Visualization Architecture for Network Operation and Management Tools [PDF]

, 2018
Recently, network operation tools using 3D visualization technologies have become more and more important. Generally, 3D visualized network operation tools are useful for computer network management or operation.
Ogashiwa, Nobuo
core  

Signatures of small-world and scale-free properties in large computer programs

, 2003
A large computer program is typically divided into many hundreds or even thousands of smaller units, whose logical connections define a network in a natural way.
A.-L. Barabási, A.-L. Barabási, A.-L. Barabási, A.-L. Barabási, A.A. Gurtovenko, A.E. Motter, A.L. Lloyd, Adilson E. Motter, Alessandro P. S. de Moura, B. Kogut, B. Kogut, B. Skyrms, B. Tadić, D.A. Fell, D.J. Watts, G. Bianconi, G. Bianconi, K.E. Stephan, L.A.N. Amaral, M. Gitterman, M.E.J. Newman, M.E.J. Newman, M.E.J. Newman, M.J. Keeling, N. Guelzim, N.E.J. Newman, P.L. Krapivsky, P.L. Krapivsky, P.L. Krapivsky, P.L. Krapivsky, R. Albert, R. Albert, R. Albert, R. Albert, S.H. Strogatz, S.N. Dorogovtsev, S.N. Dorogovtsev, S.N. Dorogovtsev, U. Blum, Ying-Cheng Lai   +39 more
core   +1 more source

A network model with structured nodes [PDF]

, 2010
We present a network model in which words over a specific alphabet, called {\it structures}, are associated to each node and undirected edges are added depending on some distance between different structures. It is shown that this model can generate, without the use of preferential attachment or any other heuristic, networks with topological features ...
arxiv   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source

ANALYSIS OF ROUTING PROTOCOLS EFFECTIVENESS IN COMPUTER NETWORKS

International Journal of Advanced Studies, 2023
The main task of networks is to transport information from the sending computer to the receiving computer. In most cases, you need to make several transfers to do this. The problem of choosing a path is solved by routing algorithms. The routing algorithm
Tatiana V. Avetisyan, Yakov E. Lvovich, Igor Ya. Lvovich, Roman A. Blinov   +3 more
doaj   +1 more source

Computer Network Specification for Distributed Spatial Data System [PDF]

, 2006
In recent years, spatial data and database become very important thing. Spatial data and database are stored into data and database server called data center.
Astika, I. W. (I), Pribadi, A. (Agus), Syafi’i, M. A. (M)   +2 more
core  

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

FEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink   +2 more
wiley   +1 more source