Results 51 to 60 of about 3,154,019 (343)

Code Building Genetic Programming [PDF]

open access: yes, 2020
In recent years the field of genetic programming has made significant advances towards automatic programming. Research and development of contemporary program synthesis methods, such as PushGP and Grammar Guided Genetic Programming, can produce programs that solve problems typically assigned in introductory academic settings.
arxiv   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Computer program determines inventory size [PDF]

open access: yes, 1966
FORTRAN 4 computer program calculates optimum size of a small inventory of relatively complex or expensive items. This program can be used in situations where the initial cost of purchase is large or when there is a need for a balanced inventory on a ...
Kaspar, H.
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

TEV—A Program for the Determination of the Thermal Expansion Tensor from Diffraction Data

open access: yesCrystals, 2015
TEV (Thermal Expansion Visualizing) is a user-friendly program for the calculation of the thermal expansion tensor αij from diffraction data. Unit cell parameters determined from temperature dependent data collections can be provided as input.
Thomas Langreiter, Volker Kahlenberg
doaj   +1 more source

Executive computer program for linking independent computer programs: ODINEX [PDF]

open access: yes, 1975
Program controls sequence of execution of network of program elements and maintains data base of common information which forms communication link among them.
Hague, D. S., Latt, C. R., Watson, D. A.
core   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

QUESTIONNAIRE AND FOLLOW-UP COMPUTER PROGRAM FOR PATIENTS WITH ENDOMETRIAL CANCER

open access: yesZdravniški Vestnik, 2004
Background. Endometrial cancer is the most frequent genital malignancy among women in Slovenia. During diagnostic and treatment procedures as well as follow-up of endometrial cancer patients after treatment, a lot of data is generated.
Iztok Takač   +5 more
doaj  

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

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