Results 91 to 100 of about 1,198,598 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Thinking processes used by high-performing students in a computer programming task

The Journal for Transdisciplinary Research in Southern Africa, 2011
Computer programmers must be able to understand programming source code and write programs that execute complex tasks to solve real-world problems. This article is a trans- disciplinary study at the intersection of computer programming, education and ...
Marietjie Havenga, R De Villiers, E Mentz   +2 more
doaj   +1 more source

Computer Programming E-Learners' Personality Traits, Self-Reported Cognitive Abilities, and Learning Motivating Factors. [PDF]

Brain Sci, 2021
Dirzyte A, Vijaikis A, Perminas A, Rimasiute-Knabikiene R, Kaminskis L, Zebrauskas G.   +5 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An Improved Similarity Measure for Interval-Valued Intuitionistic Fuzzy Numbers and Its Application to Multi-Attribute Decision-Making Problem

Mathematics
In this article, a new similarity measure is discussed on interval-valued intuitionistic fuzzy values (IVIFVs). Here, the proposed similarity measure has been derived based on transformed intervals and its probability density functions, mean values, and ...
Kartik Patra, Sanjib Sen, Shyamal Kumar Mondal   +2 more
doaj   +1 more source

An Improved Marriage in Honey Bees Optimization Algorithm for Single Objective Unconstrained Optimization

The Scientific World Journal, 2013
Marriage in honey bees optimization (MBO) is a metaheuristic optimization algorithm developed by inspiration of the mating and fertilization process of honey bees and is a kind of swarm intelligence optimizations.
Yuksel Celik, Erkan Ulker
doaj   +1 more source

Do Flipped Learning and Adaptive Instruction Improve Student Learning Outcome? A Case Study of a Computer Programming Course in Taiwan. [PDF]

Front Psychol, 2021
Chen HR, Hsu WC.
europepmc   +1 more source

Computer assisted mathematical programming [PDF]

, 1987
A Computer Assisted Mathematical Programming (Modelling) System (CAMPS) is described in this paper. The system uses program generator techniques for model creation and contrasts with earlier approaches which use a special purpose language to construct ...
Lucas, CA, Mitra, G
core  

A Visual Programming Paradigm for Abstract Deep Learning Model Development

, 2019
Deep learning is one of the fastest growing technologies in computer science with a plethora of applications. But this unprecedented growth has so far been limited to the consumption of deep learning experts.
Aralikatte, Rahul, Khare, Shreya, Mani, Senthil, Panwar, Naveen, Sankaran, Anush, Tamilselvam, Srikanth   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source