Results 121 to 130 of about 3,955,142 (302)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Gamification-based e-learning strategies for computer programming education

, 2016
Computer technologies are forever evolving and it is vital that computer science educators find new methods of teaching programming in order to maintain the rapid changes occurring in the field.
Queirós, Ricardo
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Can There Be a Two Way Hash Function?

IEEE Access
It is computationally impossible for one-way hash functions to obtain the original data again. In this study, Two Way Hash Function (TWHF) is proposed which provides the security properties of one-way hash functions. TWHF aims to hash/encrypt and decrypt
Timucin Koroglu, Refik Samet
doaj   +1 more source

An investigation into novel software tools for enhancing students' higher cognitive skills in computer programming [PDF]

Active learning is considered by many academics as an important and effective learning strategy. Students can improve the quality of their work by developing their higher cognitive skills through reflection on their own ideas, and through practice of ...
Sitthiworachart, Jirarat
core  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Redesign and validation of a computer programming course using Inductive Teaching Method. [PDF]

PLoS One, 2020
Khan IA, Iftikhar M, Hussain SS, Rehman A, Gul N, Jadoon W, Nazir B.   +6 more
europepmc   +1 more source

The First Computer Program

Communications of the ACM
Mathematician and inventor Charles Babbage's code sketches are the first attempt to specify how to mechanize complex algorithms with a computer.
openaire   +3 more sources

Design considerations of an intelligent tutoring system for programming languages [PDF]

The overall goal of the thesis is to attempt to highlight the major topics which must be considered in the design of any Intelligent Tutoring System and to illustrate their application within the particular domain of LISP programming.
Elsom-Cook, Mark
core