Results 131 to 140 of about 3,955,142 (302)

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

open access: yesFEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Structured Programming for Realtime Computer Systems [PDF]

open access: yes, 1974
University of Minnesota. University Computer Center; Patton, P. C.; Franta, W. R.. (1974). Structured Programming for Realtime Computer Systems.
University of Minnesota. University Computer Center   +2 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

An Intelligent Method for C++ Test Case Synthesis Based on a Q-Learning Agent

open access: yesApplied Sciences
Ensuring software quality during development requires effective regression testing. However, test suites in open-source libraries often grow large, redundant, and difficult to maintain. Most traditional test suite optimization methods treat test cases as
Serhii Semenov   +4 more
doaj   +1 more source

Component of programming. Theory and implementation

open access: yes, 2015
Component Programming (CP) is a kind of assembly programming, where the role played by elements of the assembly software component, or CPI, reuse, interface.
Lavrischeva, K.M.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A learning-dynamics-driven framework for robust small-object detection in complex field environments: YOLOv11l-AGRI-EMA framework

open access: yesScientific Reports
Accurate fruit detection under natural field conditions remains challenging due to small object size, occlusion, and complex background variability.
Erhan Kahya
doaj   +1 more source

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